产品名称
Anti-Blys/TALL-1/BAFF/THANK Antibody, Upstate®, from rabbit
biological source
rabbit
conjugate
unconjugated
antibody form
purified antibody
antibody product type
primary antibodies
clone
polyclonal
species reactivity
human
manufacturer/tradename
Upstate®
technique(s)
western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... TNFSF13B(10673)
Analysis Note
Control
Positive Antigen Control: Catalog #12-303, Jurkat cell lysate.
Positive Antigen Control: Catalog #12-303, Jurkat cell lysate.
routinely evaluated by immunoblot on RIPA lysates from Jurkat cells or HeLa nuclear extract
Application
Anti-Blys/TALL-1/BAFF/THANK Antibody is an antibody against Blys/TALL-1/BAFF/THANK for use in WB.
Biochem/physiol Actions
Blys/TALL-1/BAFF/THANK
General description
32kDa
Immunogen
peptide corresponding to amino acids 254-269 of human Blys (EEGDELQLAIPRENAQ)
Physical form
Format: Purified
PBS containing 0.05% BSA and 0.05% sodium azide.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
10 - Combustible liquids
Proinflammatory mediators elicit secretion of the intracellular B-lymphocyte stimulator pool (BLyS) that is stored in activated neutrophils: implications for inflammatory diseases.
Scapini, P; Carletto, A; Nardelli, B; Calzetti, F; Roschke, V; Merigo, F; Tamassia et al.
Blood null
Macrophage- and dendritic cell--dependent regulation of human B-cell proliferation requires the TNF family ligand BAFF.
Craxton, A; Magaletti, D; Ryan, EJ; Clark, EA
Blood null
Patrizia Scapini et al.
The Journal of experimental medicine, 197(3), 297-302 (2003-02-05)
B lymphocyte stimulator (BLyS) is a novel member of the TNF ligand superfamily that is important in B cell maturation and survival. We demonstrate that human neutrophils, after incubation with G-CSF or, less efficiently, IFN gamma, express high levels of
Epithelial cells trigger frontline immunoglobulin class switching through a pathway regulated by the inhibitor SLPI.
Weifeng Xu, Bing He, April Chiu, Amy Chadburn, Meimei Shan, Malwina Buldys, Aihao Ding et al.
Nature Immunology null
F Mackay et al.
The Journal of experimental medicine, 190(11), 1697-1710 (1999-12-10)
The cause of many autoimmune and inflammatory diseases is unresolved, although dysregulated production of tumor necrosis factor (TNF) family members appears to be important in many cases. BAFF, a new member of the TNF family, binds to B cells and
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