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Merck
CN

07-1815

Anti-FIP200 Antibody

serum, from rabbit

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
western blot
Species reactivity:
human, rat, mouse
Citations:
1
Technique(s):
western blot: suitable
Uniprot accession no.:
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产品名称

Anti-FIP200 Antibody, serum, from rabbit

biological source

rabbit

conjugate

unconjugated

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human, rat, mouse

technique(s)

western blot: suitable

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

Gene Information

rat ... Stx8(59074)

Analysis Note

Evaluated by western blot on HEK293 cell lysate.
Western Blot Analysis: 1:1,000 dilution of this antibody was used to detect FIP200 in HEK293 cell lysate.

Application

Detect FIP200 using this Anti-FIP200 Antibody validated for use in WB.
Research Category
Signaling
Research Sub Category
PI3K, Akt, & mTOR Signaling

Biochem/physiol Actions

This antibody recognizes the C-terminal region of FIP200.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

200 kDa
Focal adhesion kinase family interacting protein of 200 kDa (FIP200) is a novel protein inhibitor for focal adhesion kinase (FAK). FIP200 inhibits kinase activity and associated cellular functions, such as cell adhesion, spreading, and motility in fibroblasts by binding directly to FAK.

Immunogen

Epitope: C-terminus
The immunogen was a synthetic peptide corresponding to the C-terminal region of FIP200.

Physical form

Unpurified rabbit serum in buffer containing 0.05% sodium azide.

Preparation Note

Stable for 2 years at -20°C from date of receipt.
Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution.

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存储类别

10 - Combustible liquids

wgk

WGK 1


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Zhengwei Ma et al.
The Journal of clinical investigation, 130(9), 5011-5026 (2020-08-18)
Dysregulation of autophagy in diabetic kidney disease (DKD) has been reported, but the underlying mechanism and its pathogenic role remain elusive. We show that autophagy was inhibited in DKD models and in human diabetic kidneys. Ablation of autophagy-related gene 7

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