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Merck
CN

07-189

Anti-Notch 4 Antibody

Upstate®, from rabbit

别名:

Anti-INT3

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
19
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biological source

rabbit

conjugate

unconjugated

antibody form

purified antibody

antibody product type

primary antibodies

clone

polyclonal

species reactivity

mouse

manufacturer/tradename

Upstate®

technique(s)

western blot: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

Gene Information

human ... NOTCH4(4855)

General description

68kDa

Immunogen

His-tag fusion protein containing the carboxy-terminus of murine Notch 4

Application

Anti-Notch 4 Antibody is a high quality Rabbit Polyclonal Antibody for the detection of Notch 4 & has been validated in WB.

Biochem/physiol Actions

truncated, intracellular domain of Int3/Notch 4, possibly full-length Notch 4; does not cross-react with Notch 1, 2 or 3

Physical form

Format: Purified

Analysis Note

routinely evaluated by immunoblot on lysates from 293 cells transfected with the intracellular domain of murine Notch 4

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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存储类别

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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S Zhang et al.
Oncogene, 35(19), 2485-2495 (2015-08-19)
Notch controls pancreatic differentiation during development and is reactivated in pancreatic cancer. In recent years, the importance of Notch signaling in pancreatic tumorigenesis has become increasingly evident; however, it remains unclear how Notch activities are regulated in this context. Here
Notch4 normalization reduces blood vessel size in arteriovenous malformations.
Murphy, PA; Kim, TN; Lu, G; Bollen, AW; Schaffer, CB; Wang, RA
Science Translational Medicine null
Luigi Cobellis et al.
Journal of anatomy, 213(4), 464-472 (2008-08-12)
The objective of this study was to investigate the pattern of expression and the localization of Notch-1, Notch-4 and Jagged-1 in physiological and pathological human endometrium and to evaluate the expression levels of two major regulators of the G1 checkpoint
Ahmed Raafat et al.
Journal of cellular physiology, 226(7), 1940-1952 (2011-04-21)
Notch genes play a critical role in mammary gland growth, development and tumorigenesis. In the present study, we have quantitatively determined the levels and mRNA expression patterns of the Notch receptor genes, their ligands and target genes in the postnatal
Genome-wide reprogramming of the chromatin landscape underlies endocrine therapy resistance in breast cancer.
Magnani, L; Stoeck, A; Zhang, X; Lanczky, A; Mirabella, AC; Wang, TL; Gyorffy, B; Lupien, M
Proceedings of the National Academy of Sciences of the USA null

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