CN
生物来源
rabbit
质量水平
抗体形式
purified antibody
antibody product type
primary antibodies
克隆
polyclonal
species reactivity
mouse
manufacturer/tradename
Upstate®
technique(s)
western blot: suitable
同位素/亚型
IgG
NCBI登记号
UniProt登记号
运输
wet ice
target post-translational modification
unmodified
Gene Information
human ... NOTCH4(4855)
特异性
truncated, intracellular domain of Int3/Notch 4, possibly full-length Notch 4; does not cross-react with Notch 1, 2 or 3
免疫原
His-tag fusion protein containing the carboxy-terminus of murine Notch 4
应用
Anti-Notch 4 Antibody is a high quality Rabbit Polyclonal Antibody for the detection of Notch 4 & has been validated in WB.
质量
routinely evaluated by immunoblot on lysates from 293 cells transfected with the intracellular domain of murine Notch 4
目标描述
68kDa
外形
Format: Purified
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
储存分类代码
12 - Non Combustible Liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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示例
T1503
货号
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25G
包装规格/数量
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PL860-CGA/SHF-1EA
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1000309185
输入内容 1.000309185)
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未找到您寻找的产品？
部分情况下，可能未在线提供COA。如果搜索不到COA，可在线索取。
Genome-wide reprogramming of the chromatin landscape underlies endocrine therapy resistance in breast cancer.
Magnani, L; Stoeck, A; Zhang, X; Lanczky, A; Mirabella, AC; Wang, TL; Gyorffy, B; Lupien, M
Proceedings of the National Academy of Sciences of the USA null
Wen-Cheng Chung et al.
Neoplasia (New York, N.Y.), 19(11), 885-895 (2017-09-25)
Claudin-low breast cancer (CLBC) is a poor prognosis molecular subtype showing stemness and mesenchymal features. We previously discovered that deletion of a Notch signaling modulator, Lunatic Fringe (Lfng), in the mouse mammary gland induced a subset of tumors resembling CLBC.
Ahmed Raafat et al.
Journal of cellular physiology, 226(7), 1940-1952 (2011-04-21)
Notch genes play a critical role in mammary gland growth, development and tumorigenesis. In the present study, we have quantitatively determined the levels and mRNA expression patterns of the Notch receptor genes, their ligands and target genes in the postnatal
Elongin C is a mediator of Notch4 activity in human renal tubule cells.
Cummins, TD; Mendenhall, MD; Lowry, MN; Korte, EA; Barati, MT; Khundmiri, SJ; Salyer et al.
Biochimica et Biophysica Acta null
Lawrence Huang et al.
Science advances, 9(21), eade7280-eade7280 (2023-05-26)
Mechanisms underlying arteriovenous malformations (AVMs) are poorly understood. Using mice with endothelial cell (EC) expression of constitutively active Notch4 (Notch4*EC), we show decreased arteriolar tone in vivo during brain AVM initiation. Reduced vascular tone is a primary effect of Notch4*EC
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