07-2268
抗-磷酸化-TBC1D1抗体（Ser237）
from rabbit, purified by affinity chromatography
别名:
TBC1 domain family member 1, TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
产品名称
抗-磷酸化-TBC1D1抗体（Ser237）, from rabbit, purified by affinity chromatography
biological source
rabbit
conjugate
unconjugated
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
human
species reactivity (predicted by homology)
ox (based on 100% sequence homology), chimpanzee (based on 100% sequence homology), mouse (based on 100% sequence homology), rat (based on 100% sequence homology), rhesus macaque (based on 100% sequence homology)
technique(s)
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
phosphorylation (pSer237)
Quality Level
Gene Information
human ... TBC1D1(23216)
Analysis Note
对照
经λ磷酸酶处理和未处理的HEK293细胞裂解液
经λ磷酸酶处理和未处理的HEK293细胞裂解液
通过蛋白质印迹对λ磷酸酶处理和未处理的HEK293细胞裂解液进行了评估。
蛋白质印迹分析：1 µg/mL的该抗体在10 µgλ磷酸酶处理和未处理的HEK293细胞裂解液上检测到TBC1D1。
蛋白质印迹分析：1 µg/mL的该抗体在10 µgλ磷酸酶处理和未处理的HEK293细胞裂解液上检测到TBC1D1。
Application
研究子类别
胰岛素/能量信号传导
葡萄糖/糖原代谢
胰岛素/能量信号传导
葡萄糖/糖原代谢
研究类别
信号传导
信号传导
该磷酸化TBC1D1抗体经过验证可用于WB中，以用于检测磷酸化TBC1D1蛋白。
Biochem/physiol Actions
该抗体可识别在Ser237处磷酸化的TBC1D1。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
TBC1D1是包含180-220个氨基酸的tbc盒基序的蛋白质家族的第一个成员，可能与细胞生长和分化有关。TBC1D1的组成具有与已知的胰岛素介导的Glut4易位调节剂相同的功能，并且可能在严重的人类肥胖中起作用。运动后数小时，胰岛素依赖性葡萄糖转运增加归因于TBC1D1磷酸化。TBC1D1的R125W突变被认为会减少骨骼肌葡萄糖的转运，并且可能是肥胖的主要原因，而肥胖似乎与这种类型的突变有关。
观测值〜145 kDa
Immunogen
对应于在Ser237处磷酸化的人TBC1D1的KLH偶联的线性肽。
表位：磷酸化Ser237
Other Notes
浓度：请参考批次特异性浓缩物的分析证书。
Physical form
亲和纯化
纯化的兔多克隆抗体，溶于含有0.1 M Tris-甘氨酸（pH 7.4）、150 mM NaCl和0.05％叠氮化钠的缓冲液中。
Preparation Note
自收到之日起，在2-8°C条件下可稳定保存1年。
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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