一般描述
14kDa
免疫原
Peptide (GKQGGAcKARAKAK-C) corresponding to amino acids 4-15 of human Histone H2A.
应用
Anti-acetyl-Histone H2A (Lys9) Antibody is a Rabbit Polyclonal Antibody for detection of acetyl-Histone H2A (Lys9) also known as H2AK9Ac, Histone H2A (acetyl K9) & has been validated in WB.
Research Category
Epigenetics & Nuclear Function
Epigenetics & Nuclear Function
Research Sub Category
Histones
Histones
生化/生理作用
acetylated Histone 2A
外形
Antiserum
antiserum immuno-depleted with the non-acetylated immunogenic peptide, containing 0.05% sodium azide and 30% glycerol
制备说明
2 years at -20°C
分析说明
routinely evaluated by immunoblot on sodium butyrate treated acid extracted proteins from HeLa cells
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
WGK
WGK 1
Tanja Waldmann et al.
Epigenetics & chromatin, 4, 11-11 (2011-07-22)
Covalent histone modifications are central to all DNA-dependent processes. Modifications of histones H3 and H4 are becoming well characterised, but knowledge of how H2A modifications regulate chromatin dynamics and gene expression is still very limited. To understand the function of
Michael S Kobor et al.
PLoS biology, 2(5), E131-E131 (2004-03-27)
The conserved histone variant H2A.Z functions in euchromatin to antagonize the spread of heterochromatin. The mechanism by which histone H2A is replaced by H2A.Z in the nucleosome is unknown. We identified a complex containing 13 different polypeptides associated with a
Bin Wang et al.
Nature communications, 14(1), 3371-3371 (2023-06-09)
In the Neurospora circadian system, the White Collar Complex (WCC) drives expression of the principal circadian negative arm component frequency (frq). FRQ interacts with FRH (FRQ-interacting RNA helicase) and CKI, forming a stable complex that represses its own expression by inhibiting
Kyong-Rim Kieffer-Kwon et al.
Molecular cell, 67(4), 566-578 (2017-08-15)
50 years ago, Vincent Allfrey and colleagues discovered that lymphocyte activation triggers massive acetylation of chromatin. However, the molecular mechanisms driving epigenetic accessibility are still unknown. We here show that stimulated lymphocytes decondense chromatin by three differentially regulated steps. First
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