biological source
rabbit
conjugate
unconjugated
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity
rat, mouse, human
manufacturer/tradename
Upstate®
technique(s)
immunohistochemistry: suitable, immunoprecipitation (IP): suitable, western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... MAGED1(9500)
General description
90-96 kDa
Immunogen
GST fusion protein corresponding to residues 53-295 of rat MAGE-D1/NRAGE
Application
Anti-MAGE-D1/NRAGE Antibody is an antibody against MAGE-D1/NRAGE for use in IP, WB, IH.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurodegenerative Diseases
Developmental Neuroscience
Neurodegenerative Diseases
Developmental Neuroscience
Biochem/physiol Actions
NRAGE/MAGE-D1
Physical form
0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide, before the addition of glycerol to 30%
Antiserum
Preparation Note
2 years at -20°C
Analysis Note
routinely evaluated by immunoblot in RIPA lysates from PC12 cells
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
wgk
WGK 2
Amir H Salehi et al.
The Journal of biological chemistry, 277(50), 48043-48050 (2002-10-12)
The p75 neurotrophin receptor (p75NTR) mediates signaling events leading to activation of the JNK pathway and cell death in a variety of cell types. We recently identified NRAGE, a protein that directly interacts with the p75NTR cytosolic region and facilitates
A H Salehi et al.
Neuron, 27(2), 279-288 (2000-09-14)
The mechanisms employed by the p75 neurotrophin receptor (p75NTR) to mediate neurotrophin-dependent apoptosis are poorly defined. Two-hybrid analyses were used to identify proteins involved in p75NTR apoptotic signaling, and a p75NTR binding partner termed NRAGE (for neurotrophin receptor-interacting MAGE homolog)
Jennifer M Doyle et al.
Molecular cell, 39(6), 963-974 (2010-09-25)
The melanoma antigen (MAGE) family consists of more than 60 genes, many of which are cancer-testis antigens that are highly expressed in cancer and play a critical role in tumorigenesis. However, the biochemical and cellular functions of this enigmatic family
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