Anti-trimethyl Histone H3 (Lys9) Antibody, Alexa Fluor^™ 647 Conjugate

Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the ′beads on a string′ structure. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.

~17 kDa observed. Refer to Cat. No. 07-442 for observed molecular weight information.

Linear peptide corresponding to Histone H3 trimethylated at Lys9.

Research Category
Epigenetics & Nuclear Function

Research Sub Category
Histones

This Anti-trimethyl Histone H3 (Lys9) Antibody, Alexa Fluor^™ 647 Conjugate is validated for use in ICC for the detection of trimethyl Histone H3 (Lys9).

Protein A purified

Purified rabbit conjugate in buffer containing PBS, 15 mg/mL BSA, and 0.1 % Sodium Azide.

Stable for 1 year at 2-8°C from date of receipt.

Evalutated by Immunocytochemistry in HeLa cells.

Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected trimethyl Histone H3 (Lys9) in HeLa cells.

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ALEXA FLUOR is a trademark of Life Technologies

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