07-531
Anti-PIR121-1/Sra-1 Antibody
Upstate®, from rabbit
别名:
Cytoplasmic FMR1-interacting protein 1, Specifically Rac1-associated protein 1, Sra-1, p140sra-1
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IP, WB
Citations:
33
biological source
rabbit
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
species reactivity
human, mouse
manufacturer/tradename
Upstate®
technique(s)
immunoprecipitation (IP): suitable, western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... CYFIP1(23191)
mouse ... Cyfip1(20430)
General description
Mr~130kDa
Immunogen
KLH-conjugated, synthetic peptide corresponding to amino acids 872-886 (SQEFQRDKQPNAQPQ-C) of human PIR121-1/Sra-1, with a C-terminal cysteine added for conjugation purposes.
Application
Anti-PIR121-1/Sra-1 Antibody is an antibody against PIR121-1/Sra-1 for use in IP & WB.
Research Category
Apoptosis & Cancer
Apoptosis & Cancer
Research Sub Category
Apoptosis - Additional
Apoptosis - Additional
Biochem/physiol Actions
PIR121-1/Sra-1 (aka CYFIP1)
Physical form
Format: Purified
Protein A purified
Preparation Note
stable 2 years at -20°C from date of shipment
Analysis Note
routinely evaluated by immunoblot on RIPA homogenates from rat brain
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
wgk
WGK 1
S L Blagg et al.
Biochemical Society transactions, 32(Pt 6), 1113-1114 (2004-10-28)
The WASP (Wiskott-Aldrich syndrome protein)/SCAR (suppressor of cAMP receptor) family of adaptor proteins regulate actin polymerization by coupling Rho-family GTPases to the activation of the Arp2/3 complex. SCAR exists within a complex of proteins, including Nap1 (Nck-associated protein 1), PIR121
The ARP2/3 complex: giving plant cells a leading edge.
Mathur, Jaideep
Bioessays, 27, 377-387 (2005)
E Saller et al.
The EMBO journal, 18(16), 4424-4437 (1999-08-17)
p53 mutants in tumours have a reduced affinity for DNA and a reduced ability to induce apoptosis. We describe a mutant with the opposite phenotype, an increased affinity for some p53-binding sites and an increased ability to induce apoptosis. The
Local F-actin network links synapse formation and axon branching.
Chia, PH; Chen, B; Li, P; Rosen, MK; Shen, K
Cell null
Marco A Salazar et al.
The Journal of biological chemistry, 278(49), 49031-49043 (2003-09-25)
Tuba is a novel scaffold protein that functions to bring together dynamin with actin regulatory proteins. It is concentrated at synapses in brain and binds dynamin selectively through four N-terminal Src homology-3 (SH3) domains. Tuba binds a variety of actin
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