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Merck
CN

07-548

抗-单甲基-组蛋白H3(Lys36)抗体

serum, Upstate®

别名:

H3K36me1, Histone H3 (mono methyl K36)

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Technique(s):
western blot: suitable, dot blot: suitable, immunofluorescence: suitable, multiplexing: suitable
Clone:
polyclonal
Application:
DB, IF, WB, multiplexing
Citations:
8
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isotype

IgG

technique(s)

western blot: suitable, dot blot: suitable, immunofluorescence: suitable, multiplexing: suitable

biological source

rabbit

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

vertebrates

manufacturer/tradename

Upstate®

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

monomethylation (Lys36)

Quality Level

Gene Information

human ... H3F3B(3021)

General description

17kDa

Immunogen

含有对应于人组蛋白H3的单甲基赖氨酸36的序列GVmeKKP的肽。

Application

使用在DB、IF、WB、Mplex中验证的抗单甲基组蛋白H3(Lys36)抗体(兔多克隆抗体)检测单甲基组蛋白H3(Lys36),也称为H3K36me1、组蛋白H3(单甲基K36)。
研究子类别
组蛋白
研究类别
表观遗传学&核功能

Biochem/physiol Actions

单甲基组蛋白H3 (Lys36)

Physical form

0.05%叠氮化钠和30%甘油
抗血清

Preparation Note

在-20°C下可保存2年

Analysis Note

通过免疫印迹法对鸡核心组蛋白进行常规评估

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

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存储类别

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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The target of the NSD family of histone lysine methyltransferases depends on the nature of the substrate.
Li, Yan, et al.
The Journal of Biological Chemistry, 284, 34283-34295 (2009)
Changhui Sun et al.
The Plant cell, 24(8), 3235-3247 (2012-08-16)
Chromatin modifications affect flowering time in the long-day plant Arabidopsis thaliana, but the role of histone methylation in flowering time regulation of rice (Oryza sativa), a short-day plant, remains to be elucidated. We identified a late-flowering long vegetative phase1 (lvp1)
Autocatalytic differentiation of epigenetic modifications within the Arabidopsis genome.
Inagaki, S; Miura-Kamio, A; Nakamura, Y; Lu, F; Cui, X; Cao, X; Kimura, H; Saze, H; Kakutani, T
The Embo Journal null
Shuzhi Zheng et al.
Nature communications, 10(1), 1303-1303 (2019-03-23)
In plants, flowering time is controlled by environmental signals such as day-length and temperature, which regulate the floral pathway integrators, including FLOWERING LOCUS T (FT), by genetic and epigenetic mechanisms. Here, we identify an H3K27me3 demethylase, JUMONJI 13 (JMJ13), which
Han-Sae Lee et al.
The EMBO journal, 29(8), 1434-1445 (2010-03-13)
Although recent studies highlight the importance of histone modifications and ATP-dependent chromatin remodelling in DNA double-strand break (DSB) repair, how these mechanisms cooperate has remained largely unexplored. Here, we show that the SWI/SNF chromatin remodelling complex, earlier known to facilitate

相关内容

"Epigenetics describes heritable changes in gene expression caused by non-genetic mechanisms instead of by alterations in DNA sequence. These changes can be cell- or tissue-specific, and can be passed on to multiple generations. Epigenetic regulation enriches DNAbased information, allowing a cell to vary its response across diverse biological and environmental contexts. Although epigenetic mechanisms are primarily centered in the nucleus, these mechanisms can be induced by environmental signals such as hormones, nutrients, stress, and cellular damage, pointing to the involvement of cytoplasmic and extracellular factors in epigenetic regulation."

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