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UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
polyclonal
Species reactivity:
mouse, Saccharomyces cerevisiae, bovine, human
Application:
ChIP, WB, multiplexing
Citations:
50
biological source
rabbit
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity
mouse, Saccharomyces cerevisiae, bovine, human
manufacturer/tradename
Upstate®
technique(s)
ChIP: suitable, multiplexing: suitable, western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
acetylation (Lys9/Lys18)
Gene Information
human ... H3F3B(3021)
General description
17 kDa
组蛋白H3是参与真核细胞染色质结构的5种主要组蛋白之一。H3具有一个主要的球状结构域和一个长N末端的尾巴,其与核糖体核小体′串珠′结构体的结构有关。
组蛋白H3的乙酰化发生在组蛋白尾部的几个不同的赖氨酸位置,并由称为组蛋白乙酰基转移酶(HATs)的酶家族完成。
组蛋白H3的乙酰化发生在组蛋白尾部的几个不同的赖氨酸位置,并由称为组蛋白乙酰基转移酶(HATs)的酶家族完成。
Immunogen
肽(ARAcKSTGGKAPRAcKQ),对应于人组蛋白H3第9和18位残基的乙酰赖氨酸
Application
抗乙酰化组蛋白H3(Lys9/18)抗体是一种兔多克隆抗体,用于检测乙酰化组蛋白H3(Lys9/18)(也称为H3K9/18Ac,组蛋白H3(乙酰基K9/18)),& 已经过验证可用于ChIP、WB、Mplex。
研究子类别
组蛋白
组蛋白
研究类别
表观遗传学&核功能
表观遗传学&核功能
Biochem/physiol Actions
识别赖氨酸9和18乙酰化的组蛋白H3。
预计具有广泛的物种交叉反应性
Physical form
未纯化
蛋白A纯化的免疫球蛋白,溶于30%甘油,0.07M Tris-甘氨酸(pH 7.4)、0.105 M NaCl,0.035%叠氮化钠作为防腐剂的溶液中。
Preparation Note
自收到之日起在-20°C可稳定保存2年。避免反复冻融。为了最大程度地回收产品,在融化后和取下盖子之前,将原始样品瓶进行离心。
Analysis Note
对照
经丁酸钠处理过的HeLa细胞的酸提取物
经丁酸钠处理过的HeLa细胞的酸提取物
通过免疫印迹法对丁酸钠处理的HeLa细胞的酸提取物进行了常规评估(目录#17-305)
Other Notes
浓度:请参考批次特异性浓缩物的分析证书。
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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Tissue & cell null
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