07-601
抗TTF-1抗体
serum, Upstate®
别名:
Anti-BCH, Anti-BHC, Anti-NK-2, Anti-NKX2.1, Anti-NKX2A, Anti-NMTC1, Anti-T/EBP, Anti-TEBP, Anti-TITF1, Anti-TTF-1, Anti-TTF1
生物来源
rabbit
偶联物
unconjugated
抗体形式
serum
抗体产品类型
primary antibodies
克隆
polyclonal
种属反应性
mouse, rat, human
制造商/商品名称
Upstate®
技术
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
同位素/亚型
IgG
NCBI登记号
UniProt登记号
运输
wet ice
靶向翻译后修饰
unmodified
基因信息
human ... A1CF(29974)
一般描述
42kDa
免疫原
对应于全长TTF-1的6His融合蛋白（甲状腺转录因子1，也称为甲状腺核因子1，同源盒蛋白Nkx-2.1）
应用
抗TTF-1抗体是一种高质量的兔多克隆抗体，用于检测TTF-1，&已在IP、WB & IHC中得到验证。
研究子类别
转录因子
转录因子
研究类别
表观遗传学&核功能
表观遗传学&核功能
生化/生理作用
TTF-1
外形
兔抗血清，含有0.05%叠氮化钠，然后添加甘油至30%
血清
制备说明
在-20°C下可保存2年
分析说明
通过免疫印迹法对H441人肺上皮细胞的核提取物进行了常规评估
其他说明
替代：MABE513
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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储存分类代码
12 - Non Combustible Liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Epigenetic mechanisms modulate thyroid transcription factor 1-mediated transcription of the surfactant protein B gene.
Yuxia Cao,Tiffany Vo,Guetchyn Millien,Jean-Bosco Tagne,Darrell Kotton,Robert J Mason et al.
The Journal of Biological Chemistry null
A Khoor et al.
Human pathology, 30(6), 695-700 (1999-06-22)
Differentiation of malignant mesothelioma from adenocarcinoma, particularly from a lung primary, remains a difficult diagnostic problem. Surfactant protein B precursor (pro-SP-B) and thyroid transcription factor 1 (ITF-1) are expressed selectively in the normal respiratory epithelium and in adenocarcinomas of the
R J Bohinski et al.
Journal of neuro-oncology, 40(3), 227-231 (1999-03-05)
Determining the primary site of a cerebral metastatic adenocarcinoma is complicated by the histologic similarity of most adenocarcinomas. Thyroid Transcription Factor-1 (TTF-1) is a highly specific marker of peripheral airway cell neoplasms. Formalin fixed tissue from 30 patients with brain
Mario DeFelice et al.
The Journal of biological chemistry, 278(37), 35574-35583 (2003-06-28)
Thyroid transcription factor-1 (TTF-1) is a 43-kDa, phosphorylated member of the Nkx2 family of homeodomain-containing proteins expressed selectively in lung, thyroid, and the central nervous system. To assess the role of TTF-1 and its phosphorylation during lung morphogenesis, mice bearing
Eric P Knott et al.
Cells, 13(13) (2024-07-12)
Understanding tumor-host immune interactions and the mechanisms of lung cancer response to immunotherapy is crucial. Current preclinical models used to study this often fall short of capturing the complexities of human lung cancer and lead to inconclusive results. To bridge
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