一般描述
220kDa
免疫原
fusion protein corresponding to residues 1595-1630 of human Scrib
应用
Detect Scrib using this Anti-Scrib Antibody validated for use in WB.
Research Category
Signaling
Signaling
Research Sub Category
Growth Factors & Receptors
Growth Factors & Receptors
生化/生理作用
Scrib
外形
Protein A purified
70% storage buffer (0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide) and 30% glycerol.
Format: Purified
制备说明
2 years at -20°C
分析说明
routinely evaluated by immunoblot from HeLa cells
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
WGK
WGK 1
Victoria M Wu et al.
Current opinion in cell biology, 16(5), 493-499 (2004-09-15)
The size of epithelial tubes is critical for the function of organs such as the lung, kidney and vascular system. However, the molecular mechanisms regulating tube size are largely unknown. Recent work in the Drosophila tracheal system reveals that septate
Patrick Humbert et al.
BioEssays : news and reviews in molecular, cellular and developmental biology, 25(6), 542-553 (2003-05-27)
Dlg (Discs large), Scrib (Scribble) and Lgl (Lethal giant larvae) are evolutionarily conserved components of a common genetic pathway that link the seemingly disparate functions of cell polarity and cell proliferation in epithelial cells. dlg, scrib and lgl have been
Yiping Huang et al.
Cell cycle (Georgetown, Tex.), 7(11), 1613-1622 (2008-05-13)
Epithelial-to-mesenchymal transition (EMT) underlies cell plasticity and embryonic development and is frequently observed in advanced tumorigenesis. We demonstrated that midkine (MK), a retinoic acid-inducible heparin-binding mitogen, promotes EMT in immortalized HaCaT keratinocytes. We showed that MK binds to the Notch2
S Nakagawa et al.
Molecular and cellular biology, 20(21), 8244-8253 (2000-10-12)
The high-risk human papillomavirus (HPV) E6 proteins stimulate the ubiquitination and degradation of p53, dependent on the E6AP ubiquitin-protein ligase. Other proteins have also been shown to be targeted for degradation by E6, including hDlg, the human homolog of the
Eirini M Kallimasioti-Pazi et al.
PLoS biology, 16(12), e2005595-e2005595 (2018-12-13)
Genome editing occurs in the context of chromatin, which is heterogeneous in structure and function across the genome. Chromatin heterogeneity is thought to affect genome editing efficiency, but this has been challenging to quantify due to the presence of confounding
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