产品名称
抗APP抗体, Upstate®, from rabbit
biological source
rabbit
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
human, rat, mouse
species reactivity (predicted by homology)
chimpanzee (based on 100% sequence homology), primate (based on 100% sequence homology)
manufacturer/tradename
Upstate®
technique(s)
immunoprecipitation (IP): suitable, western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... APP(351)
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General description
110kDa
Immunogen
与人淀粉样前体蛋白(APP)的44-61位氨基酸对应的合成肽
Application
抗APP抗体可检测APP水平&,已发表 &并经过验证可用于IP &WB。
研究子类别
泛素 & 泛素代谢
神经退行性疾病
泛素 & 泛素代谢
神经退行性疾病
研究类别
神经科学
神经科学
Biochem/physiol Actions
APP
Physical form
免疫亲和纯化
纯化的兔多克隆抗体,溶于含有0.1 M Tris-甘氨酸(pH 7.4)、150 mM NaCl和0.05%叠氮化钠的缓冲液中。
Preparation Note
自收到之日起,在2-8°C条件下可稳定保存1年。
Analysis Note
已通过免疫印迹进行常规评估。
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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存储类别
10 - Combustible liquids
wgk
WGK 1
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Distinct presenilin-dependent and presenilin-independent gamma-secretases are responsible for total cellular Abeta production.
Wilson, Christina A, et al.
Journal of Neuroscience Research, 74, 361-369 (2003)
CSF markers for Alzheimer's disease: total tau, phospho-tau and Abeta42.
Andreasen, Niels, et al.
The World Journal of Biological Psychiatry : The Official Journal of the World Federation of Societies of Biological Psychiatry, 4, 147-155 (2003)
Role of acyl-coenzyme a: cholesterol acyltransferase activity in the processing of the amyloid precursor protein.
Puglielli, Luigi, et al.
Journal of Molecular Neuroscience, 24, 93-96 (2004)
Ubiquitin over-expression phenotypes and ubiquitin gene molecular misreading during aging in Drosophila melanogaster.
Hoe, N; Huang, CM; Landis, G; Verhage, M; Ford, D; Yang, J; van Leeuwen, FW; Tower, J
Aging null
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