biological source
rabbit
conjugate
unconjugated
antibody form
purified antibody
antibody product type
primary antibodies
Gene Information
human ... ROR1(4919)
species reactivity
monkey, mouse, rat, human
manufacturer/tradename
Upstate®
technique(s)
western blot: suitable
isotype
IgG
NCBI accession no.
shipped in
wet ice
target post-translational modification
unmodified
General description
Mr 21kDa
Immunogen
KLH缀合的合成肽，对应于人Sar1（a和b亚型）的氨基酸46-62（CKDDRLGQHVPTLHPTSE），其N端添加有半胱氨酸以进行缀合
Application
抗Sar1抗体经过验证可用在WB中检测Sar1。
研究子类别
G-蛋白
激酶 & 磷酸酶
G-蛋白
激酶 & 磷酸酶
研究类别
信号传导
信号传导
Biochem/physiol Actions
Sar1
Physical form
形式：纯化
蛋白A纯化
Preparation Note
自运送之日起在-20°C下稳定保存2年
Analysis Note
对照
阳性抗原对照：货号12-305，3T3/A31裂解液。添加2.5 μL 2-巯基乙醇/100 μL裂解液，煮沸5分钟以还原 制剂。在微凝胶每个泳道上样20 μg经还原的裂解液。
阳性抗原对照：货号12-305，3T3/A31裂解液。添加2.5 μL 2-巯基乙醇/100 μL裂解液，煮沸5分钟以还原 制剂。在微凝胶每个泳道上样20 μg经还原的裂解液。
已通过免疫印迹法对3T3/A31细胞的RIPA裂解液进行了常规评估
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
The intracellular transport of chylomicrons requires the small GTPase, Sar1b.
Shoulders, Carol C, et al.
Current Opinion in Lipidology, 15, 191-197 (2004)
A structural view of the COPII vesicle coat.
Bickford, Lincoln C, et al.
Current Opinion in Structural Biology, 14, 147-153 (2004)
Xue-Hai Liang et al.
Nucleic acids research, 46(19), 10225-10245 (2018-09-22)
RNase H1-dependent, phosphorothioate-modified antisense oligonucleotides (PS-ASOs) can enter cells through endocytic pathways and need to be released from the membrane-enclosed organelles, a limiting step for antisense activity. Accumulating evidence has suggested that productive PS-ASO release mainly occurs from late endosomes
François-Xavier Campbell-Valois et al.
Molecular & cellular proteomics : MCP, 11(7), M111-M111 (2012-03-20)
Phagosomes, by killing and degrading pathogens for antigen presentation, are organelles implicated in key aspects of innate and adaptive immunity. Although it has been well established that phagosomes consist of membranes from the plasma membrane, endosomes, and lysosomes, the notion
Bethan Jones et al.
Nature genetics, 34(1), 29-31 (2003-04-15)
Dietary fat is an important source of nutrition. Here we identify eight mutations in SARA2 that are associated with three severe disorders of fat malabsorption. The Sar1 family of proteins initiates the intracellular transport of proteins in COPII (coat protein)-coated
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