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Anti-HRI Antibody
serum, Upstate®
别名:
Anti-HCR, Anti-HRI, Anti-LEMSPAD, Anti-hHRI
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IP, WB
Citations:
18
biological source
rabbit
conjugate
unconjugated
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity
rabbit, human, mouse
manufacturer/tradename
Upstate®
technique(s)
immunoprecipitation (IP): suitable, western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... EIF2AK1(27102)
mouse ... Eif2Ak1(15467)
General description
72kDa
Immunogen
6His-tagged fusion protein corres-ponding to residues 1-138 of mouse heme-regulated inhibitor (HRI)
Application
Detect HRI using this Anti-HRI Antibody validated for use in IP & WB.
Biochem/physiol Actions
HRI
Analysis Note
Routinely evaluated by immunoblot on lysates from mouse reticulocytes.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
J J Chen et al.
Trends in biochemical sciences, 20(3), 105-108 (1995-03-01)
Protein synthesis is regulated by the phosphorylation of the alpha-subunit of eukaryotic initiation factor 2 (eIF-2 alpha) in a variety of cells. At present, there are two distinct mammalian eIF-2 alpha kinases that have been cloned, the double-stranded-RNA-dependent eIF-2 alpha
Takahiro Sakai et al.
Antioxidants (Basel, Switzerland), 10(9) (2021-09-29)
Lung fibrosis is the primary pathology in idiopathic pulmonary fibrosis and is considered to result from an increase in reactive oxygen species (ROS) levels in alveolar epithelial cells. However, the exact mechanism underlying lung fibrosis remains unclear and there is
The eIF-2alpha kinases and the control of protein synthesis.
de Haro, C, et al.
Faseb Journal, 10, 1378-1387 (1996)
Maryam Rafie-Kolpin et al.
Biochemistry, 42(21), 6536-6544 (2003-05-28)
In heme deficiency, protein synthesis is inhibited by the activation of the heme-regulated eIF2alpha kinase (HRI) through its multiple autophosphorylation. Autophosphorylation sites in HRI were identified in order to investigate their functions. We found that there were eight major tryptic
D L Baggesen et al.
Journal of applied microbiology, 103(3), 650-656 (2007-08-24)
To analyse the relative importance of different biological and technical factors on the analytical sensitivity of conventional culture methods for detection of Salmonella Dublin in cattle faeces. Faeces samples collected from six adult bovines from different salmonella-negative herds were split
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