产品名称
Anti-monomethyl-Histone H4 (Lys20) Antibody, Upstate®, from rabbit
biological source
rabbit
antibody form
purified antibody
antibody product type
primary antibodies
clone
polyclonal
species reactivity
human
manufacturer/tradename
Upstate®
technique(s)
immunocytochemistry: suitable
multiplexing: suitable
western blot: suitable
isotype
IgG
NCBI accession no.
shipped in
wet ice
target post-translational modification
monomethylation (Lys20)
Quality Level
Gene Information
human ... HIST2H4B(554313)
Application
Additional Referenced Research Applications:
Immunocytochemistry (cells)
Immunocytochemistry (cells)
Anti-monomethyl-Histone H4 (Lys20) Antibody is a rabbit polyclonal antibody for detection of monomethyl-Histone H4 (Lys20) also known as H4K20me1, Histone H4 (mono methyl K20) & has been validated in WB, Mplex, ICC.
Research Category
Epigenetics & Nuclear Function
Epigenetics & Nuclear Function
Research Sub Category
Histones
Histones
Analysis Note
Routinely evaluated by immunoblot
Biochem/physiol Actions
Broad species cross-reactivity expected due to sequence conservation
monomethylated Histone H4 (Lys20)
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
10kDa
Immunogen
KLH-conjugated, branched synthetic peptide corresponding to amino acids 15-25 (AKRHR[me1K]VLRDN) of human Histone H4
Physical form
0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide and 30% glycerol.
Format: Purified
Protein A purified
Preparation Note
2 years at -20°C from date of shipment
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
10 - Combustible liquids
wgk
WGK 1
Li Liu et al.
PloS one, 8(11), e78253-e78253 (2013-11-14)
The upstream Gγ-globin cAMP-response element (G-CRE) plays an important role in regulating Gγ-globin expression through binding of ATF2 and its DNA-binding partners defined in this study. ATF2 knockdown resulted in a significant reduction of γ-globin expression accompanied by decreased ATF2
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