生物来源
rabbit
质量水平
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
纯化方式
affinity chromatography
种属反应性
human, mouse, rat
制造商/商品名称
Upstate®
技术
ELISA: suitable
western blot: suitable
同位素/亚型
IgG
NCBI登记号
UniProt登记号
运输
dry ice
靶向翻译后修饰
phosphorylation (pTyr245)
基因信息
human ... ABI1(10006)
mouse ... Abi1(11308)
rat ... Abi1(79249)
一般描述
145 kDa (210 kDa for BCR-Abl)
免疫原
KLH-conjugated peptide corresponding to amino acid region encompassing human c-Abl Tyr245.
应用
Anti-phospho-Abl (Tyr245) Antibody is an antibody against phospho-Abl (Tyr245) for use in ELISA & WB.
Research Category
Signaling
Signaling
Research Sub Category
Cytoskeletal Signaling
General Post-translation Modification
Cytoskeletal Signaling
General Post-translation Modification
生化/生理作用
Other species have not been tested.
Recognizes both Abl and BCR-Abl when phosphorylated on tyrosine residue corresponding to Tyr245 in Abl.
外形
ImmunoAffinity Purified
分析说明
Routinely evaluated by immunoblot.
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
12 - Non Combustible Liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
A common phosphotyrosine signature for the Bcr-Abl kinase
Goss, Valerie L, et al
Blood, 107, 4888-4897 (2006)
Phosphotyrosine mapping in Bcr/Abl oncoprotein using phosphotyrosine-specific immonium ion scanning
Steen, Hanno, et al
Molecular and Cellular Proteomics, 2, 138-145 (2003)
Phosphoproteomic analysis of AML cell lines identifies leukemic oncogenes
Walters, Denise K, et al
Leukemia Research, 30, 1097-1104 (2006)
Anna Stenqvist et al.
Neuroscience letters, 435(1), 11-16 (2008-03-21)
Ret is a receptor tyrosine kinase for the GDNF family of ligands and plays important roles during nervous system development for cell proliferation, cell migration and neurite growth. Signaling initiated from intracellular tyrosine 1062, by recruitment of several different phosphotyrosine
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