biological source
rabbit
antibody form
affinity purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
mouse, human
manufacturer/tradename
Upstate®
technique(s)
western blot: suitable
isotype
IgG
NCBI accession no.
shipped in
dry ice
target post-translational modification
phosphorylation (pTyr754)
Quality Level
Gene Information
human ... PDGFRA(5156)
General description
170-185 kDA
The previously assigned protein identifier Q9UD28 has been merged into P16234. Full details can be found on the UniProt database.
Immunogen
Peptide corresponding to amino acid region encompassing the human phospho-PDGFRα (Tyr754).
Application
Research Category
Signaling
Signaling
Research Sub Category
Growth Factors & Receptors
Growth Factors & Receptors
This Anti-phospho-PDGFRα (Tyr754) Antibody is validated for use in WB for the detection of phospho-PDGFRα (Tyr754).
Biochem/physiol Actions
Human and Mouse PDGFRα that is phosphorylated on Tyrosine 754 and 762, respectively. Rat is predicted to react based on sequence homology.
Predicted to cross-react with rat based on 100% sequence similarity, but has not been tested.
Physical form
100 μL of affinity purified rabbit polyclonal IgG in buffer (PBS (without Mg2+ and Ca2+), pH 7.4 containing 1.0 mg/mL BSA (IgG, protease free) and 0.05% sodium azide).
Affinity purified
Preparation Note
2 years at -80°C.
Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -80°C. Avoid repeated freeze/ thaw cycles, which may damage IgG and affect product performance.
Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -80°C. Avoid repeated freeze/ thaw cycles, which may damage IgG and affect product performance.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulation of platelet-derived growth factor receptor function by integrin-associated cell surface transglutaminase.
Zemskov, EA; Loukinova, E; Mikhailenko, I; Coleman, RA; Strickland, DK; Belkin, AM
The Journal of Biological Chemistry null
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