09-274
抗-PEAK1抗体
from rabbit, purified by affinity chromatography
别名:
NKF3 kinase family member, Sugen kinase 269
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
4
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
human
technique(s)
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... PEAK1(79834)
General description
250kda
PEAK1属于蛋白激酶超家族。PEAK1也称酪氨酸蛋白激酶SgK269和Sugen激酶269。它包含一个分叉的、可能没有活性的真核蛋白激酶结构域。它有一个旁系同源物，也称SgK223或pragmin。 这两者构成了蛋白激酶NKF3亚家族，存在于脊椎动物和棘皮动物中。
Immunogen
表位：1511-1660 aa
重组蛋白，aa：1511-1660。同源性：100% 人和黑猩猩； 96% 猪和马；90%小鼠；88%大鼠
Application
该抗-PEAK1抗体经过验证可用于WB检测PEAK1。
Biochem/physiol Actions
其他物种尚未经过测试。
Analysis Note
对照
FG Nonstim /Nonstrvd 裂解液
FG Nonstim /Nonstrvd 裂解液
通过蛋白质印迹在FG Nonstim /Nonstrvd裂解液中进行了常规评估。
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Exosome-delivered circSATB2 targets the miR-330-5p/PEAK1 axis to regulate proliferation, migration and invasion of lung cancer cells.
Zhu, et al.
Thoracic cancer, 13, 3007-3017 (2023)
Ken Fujimura et al.
Cancer research, 78(6), 1444-1456 (2018-01-13)
There remains intense interest in tractable approaches to target or silence the KRAS oncoprotein as a rational therapeutic strategy to attack pancreatic ductal adenocarcinoma (PDAC) and other cancers that overexpress it. Here we provide evidence that accumulation of the KRAS
Kristina Y Aguilera et al.
Molecular cancer therapeutics, 16(11), 2473-2485 (2017-09-03)
The extracellular matrix (ECM), a principal component of pancreatic ductal adenocarcinoma (PDA), is rich in fibrillar collagens that facilitate tumor cell survival and chemoresistance. Discoidin domain receptor 1 (DDR1) is a receptor tyrosine kinase that specifically binds fibrillar collagens and
Collagen signaling enhances tumor progression after anti-VEGF therapy in a murine model of pancreatic ductal adenocarcinoma.
Aguilera, KY; Rivera, LB; Hur, H; Carbon, JG; Toombs, JE; Goldstein, CD; Dellinger et al.
Cancer Research null
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