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Merck
CN

09-817

Sigma-Aldrich

抗-JMJD1抗体

from rabbit, purified by affinity chromatography

别名:

JMJD, jumonji domain containing 1C, TR-interacting protein 8, thyroid receptor interacting protein 8, probable JmjC domain-containing histone demethylation protein 2C, thyroid hormone receptor interactor 8, Thyroid receptor-interacting protein 8, Jumonji

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关于此项目

UNSPSC代码:
12352203
eCl@ss:
32160702
NACRES:
NA.41

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生物来源

rabbit

质量水平

100

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

纯化方式

affinity chromatography

种属反应性

human

种属反应性（根据同源性预测）

chimpanzee (based on 100% sequence homology), rhesus macaque (based on 100% sequence homology), orangutan (based on 100% sequence homology), rabbit (based on 100% sequence homology)

技术

immunocytochemistry: suitable
western blot: suitable

NCBI登记号

NP_116165

UniProt登记号

Q15652

运输

wet ice

靶向翻译后修饰

unmodified

基因信息

human ... JMJD1C(221037)

一般描述

JMJD1C（含jumonji域的蛋白1C）也称TRIP8，该组蛋白脱甲基酶的突变与某些形式的自闭症有关。JMJD1C也被认为可以重新激活胚胎干细胞、胰岛和胃癌中的基因。JMJD1C也被认为是基因表达调节剂。最近显示带有WHISTLE的JMJD1C在小鼠睾丸发育中也起作用。JMJD1C已被确定为核受体共激活因子，并且是自闭症的候选基因。
观测值〜284 kDa

免疫原

对应于人JMJD1C的KLH偶联线性肽。

应用

使用经WB、ICC验证的抗-JMJD1C抗体（兔多克隆抗体）检测JMJD1C，也称为含1C或tr相互作用蛋白8的jumonji结构域。
免疫细胞化学分析： 来自代表性批次的1:500稀释液在HeLa细胞中检测到JMJD1C。
研究子类别
组蛋白修饰蛋白
研究类别
表观遗传学&核功能

外形

亲和纯化
纯化的兔多克隆抗体，溶于含有0.1 M Tris-甘氨酸（pH 7.4）、150 mM NaCl和0.05％叠氮化钠的缓冲液中。

制备说明

自收到之日起，在2-8°C条件下可稳定保存1年。

分析说明

对照
HeLa核提取物
通过蛋白质印迹对HeLa核提取物进行了评估。

蛋白质印迹分析：1 µg/mL的该抗体在10 µg HeLa核提取物中检测到JMJD1C。

其他说明

浓度：请参考批次特异性浓缩物的检验报告。

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储存分类代码

12 - Non Combustible Liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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