biological source
Serratia marcescens
recombinant
expressed in E. coli
sterility
non-sterile
assay
≥90% (SDS-PAGE)
form
buffered aqueous glycerol solution
specific activity
≥250 units, pH 8.0, 37 °C
concentration
≥250 units/μL
impurities
≤10 CFU in 100 000 U Colony count (Yeasts and moulds)
≤10 CFU in 100 000 U Colony count (aerobic bacteria)
not detectable Proteases
color
clear
colorless
pH
8 (25 °C in H2O)
application(s)
pharma/biopharma processes
foreign activity
foreign activity ≥1.0 x 10^6 units (calc. on protein)
shipped in
dry ice
storage temp.
−20°C
Quality Level
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Application
用于去除蛋白样品中的核酸。
Benzonase® purity grade II (>90%) for biotechnology is the technical grade in our Benzonase® product portfolio. All Benzonase® endonuclease products share the same amino acid sequence (proven by LC-MS/MS mass spectrometry), robustness and activity. The technical grade can be used to optimize the production / testing process before using one of our GMP grade during verification and manufacturing process.
Biochem/physiol Actions
消化天然或热变性的DNA和RNA。
General description
Our comprehensive portfolio of downstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.
We offer a range of high quality critical raw materials plus the documentation and expertise to help our customers meet stringent regulatory requirements. Our SAFC® portfolio of high-quality products withstands strict quality control procedures.
Packaging
500,000 Units5,000,000 Units
Legal Information
Benzonase is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
10 - Combustible liquids
wgk
WGK 1
法规信息
新产品
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Benzonase®endonuclease efficiently removes nucleic acid contaminants from viral production, crucial for cell and gene therapies and vaccines.
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