Merck
CN
所有图片(2)

文件

1.06756

SAFC

4-羟基苯甲酸甲酯钠盐

EMPROVE® ESSENTIAL, Ph. Eur., BP, NF

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别名:
Methyl 4-hydroxybenzoate sodium salt, 4-Hydroxybenzoic acid methyl ester sodium salt, Methylparaben sodium salt
线性分子式:
Na+[4-(O)C6H4(COOCH3)]-
CAS号:
5026-62-0
分子量:
174.13
MDL编号:
MFCD00016470
EC索引号:
225-714-1

Agency

BP
NF
Ph. Eur.

质量水平

500

产品线

EMPROVE® ESSENTIAL

形式

solid

自燃温度

>600 °C

pH值（酸碱度）

9.7-10.3 (1 g/L in H2O)

mp

>125 °C

密度

1.42 g/cm3 at 20 °C

application(s)

liquid formulation
ophthalmics
pharmaceutical
semi-solid formulation
solid formulation

储存温度

15-25°C

InChI

1S/C8H8O3.Na/c1-11-8(10)6-2-4-7(9)5-3-6;/h2-5,9H,1H3;/q;+1/p-1

InChI key

PESXGULMKCKJCC-UHFFFAOYSA-M

相关类别

一般描述

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

应用

Methyl 4-hydroxybenzoate has antimicrobial characteristics and is used as preservative in pharmaceutical formulations and cosmetics. It can be combined with other parabens like propyl 4-hydroxybenzoate or ethyl 4-hydroxybenzoate. The sodium salt provides improved solubility in water compared to standard methyl 4-hydroxybenzoate.

法律信息

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.

象形图

Corrosion
GHS05

警示用语：

Danger

危险声明

H315 - H318 - H412

危险分类

Aquatic Chronic 3 - Eye Dam. 1 - Skin Irrit. 2

储存分类代码

11 - Combustible Solids

WGK

WGK 1

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Ambra Masuzzo et al.
eLife, 8 (2019-10-30)
When facing microbes, animals engage in behaviors that lower the impact of the infection. We previously demonstrated that internal sensing of bacterial peptidoglycan reduces Drosophila female oviposition via NF-κB pathway activation in some neurons (Kurz et al., 2017). Although we

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