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Merck
CN

1.09334

LiChrosorb® RP-18 (10 µm) HPLC Columns

HPLC sorbent

别名:

TM=["LiChrosorb"] C18 sorbent for HPLC

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UNSPSC Code:
41115709
NACRES:
SB.52
Particle size:
10 μm
Matrix active group:
C18 bonding phase
Pore size:
100 Å pore size
Matrix:
fully porous particle

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产品名称

LiChrosorb® RP-18 (10 µm),

material

stainless steel column

agency

suitable for USP L1

product line

LiChrosorb®

feature

endcapped: no

parameter

60 °C max. temp.

technique(s)

HPLC: suitable, mass spectrometry (MS): suitable (Low)

matrix

fully porous particle

matrix active group

C18 bonding phase

particle size

10 μm

pore size

100 Å pore size

operating pH range

2-7.5

bulk density

200‑400 kg/m3

separation technique

reversed phase

storage temp.

no temp limit

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Application


  • High-performance liquid chromatographic determination of the antifungal drug fluconazole in plasma and saliva of human immunodeficiency virus-infected patients.: This study highlights a method using RP-18 for the determination of fluconazole, demonstrating the column′s effectiveness in bioanalytical contexts (Beijnen JH et al., 1995).

  • Determination of serum aluminium using an ion-pair reversed-phase high-performance liquid chromatographic-fluorimetric system with lumogallion.: This research utilizes RP-18 to analyze serum aluminum, showcasing its utility in trace metal analysis in clinical samples (Ong CN et al., 1995).

  • A radiochemical high-performance liquid chromatographic method for the analysis of 2-fluoro-2-deoxy-D-glucose-derived metabolites in human chondrocytes.: The method developed employs RP-18, underscoring its role in the radiochemical analysis of complex biological matrices (Greiling H et al., 1993).

  • Systematic approach to the determination of cephalosporins in biological fluids by reversed-phase liquid chromatography.: This study demonstrates the application of RP-18 in the pharmacokinetic analysis of cephalosporins, further proving the column′s broad applicability in pharmaceutical analyses (Juge F et al., 1983).

  • Simultaneous determination of 3,4-dihydroxyphenylalanine, 5-hydroxytryptophan, dopamine, 4-hydroxy-3-methoxyphenylalanine, norepinephrine, 3,4-dihydroxyphenylacetic acid, homovanillic acid, serotonin, and 5-hydroxyindoleacetic acid in rat cerebrospinal fluid and brain by high-performance liquid chromatography with electrochemical detection.: This research uses RP-18 to simultaneously quantify multiple neurotransmitters, highlighting its sensitivity and specificity for neurochemical analysis (Huot S et al., 1982).


Analysis Note

Theoretical Plates (N/m) (Toluene): ≥ 25000
stability testing (performance): passes test
particle size (Malvern) (d10): 8.7 - 10.0 µm
particle size (Malvern) (d50): 12.0 - 14.0 µm
particle size (Malvern) (d90): 17.5 - 20.5 µm

Legal Information

LiChrosorb is a registered trademark of Merck KGaA, Darmstadt, Germany

存储类别

11 - Combustible Solids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

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