InChI
1S/O2Si/c1-3-2
SMILES string
O=[Si]=O
InChI key
VYPSYNLAJGMNEJ-UHFFFAOYSA-N
material
silica gel (irregularly-shaped)
product line
LiChroPrep®
potency
>5000 mg/kg LD50, skin (Rabbit)
matrix active group
Irregular-Shaped Silica Gel
particle size
15-40 μm
pore size
6 nm mean pore size
pH
7 (20 °C, 100 g/L in H2O, slurry)
bp
2230 °C (lit.)
mp
>1600 °C (lit.)
bulk density
200‑800 kg/m3
application(s)
pharma/biopharma processes
plasma purification
separation technique
reversed phase
storage temp.
no temp limit
Quality Level
General description
Irregular-shaped Silica gel with narrow, well defined particle size distribution delivering high separating performance, permeability and good reproducibility
Application
LiChroprep Si 60 (15-25 µm) for liquid chromatography. CAS 7631-86-9, EC Number 231-545-4, chemical formula SiO₂.
Features and Benefits
LiChroprep® Si 60 (15-25 µm) provides users with:
- Reproducible, homogeneous, irregularly shaped silica gel matrix
- Narrow, well defined particle size distribution for high performance and high permeability
- Large batch sizes up to 200 kg in the modification
Packaging
Plastic bottle
Analysis Note
pH-value (10 % suspension): 6.5 - 7.5
Loss on drying (150 °C): 5.5 - 6.5 %
Specific surface area (according to BET): 480 - 540 m²/g
Pore volume (N₂-isotherm): 0.74 - 0.84 ml/g
particle size (Malvern) (d10): 11.0 - 16.0 µm
particle size (Malvern) (d50): 18.0 - 24.0 µm
particle size (Malvern) (d90): 27.0 - 37.0 µm
Application test (2-Nitrotoluene): conforms
Pressure: ≤ 15.0 bar
Separation efficiency (2-Nitrotoluene): ≥ 8000
Leading: ≤ 7 %
Tailing: ≤ 11 %
Symmetry: 0.8 - 1.5
Capacity factor: ≥ 0.3
The specific surface is related to silica gel raw material.
Loss on drying (150 °C): 5.5 - 6.5 %
Specific surface area (according to BET): 480 - 540 m²/g
Pore volume (N₂-isotherm): 0.74 - 0.84 ml/g
particle size (Malvern) (d10): 11.0 - 16.0 µm
particle size (Malvern) (d50): 18.0 - 24.0 µm
particle size (Malvern) (d90): 27.0 - 37.0 µm
Application test (2-Nitrotoluene): conforms
Pressure: ≤ 15.0 bar
Separation efficiency (2-Nitrotoluene): ≥ 8000
Leading: ≤ 7 %
Tailing: ≤ 11 %
Symmetry: 0.8 - 1.5
Capacity factor: ≥ 0.3
The specific surface is related to silica gel raw material.
Legal Information
LICHROPREP is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
13 - Non Combustible Solids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
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