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关于此项目
经验公式(希尔记法):
C11H16N4O4
化学文摘社编号:
分子量:
268.27
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.54
Assay:
≥98% (HPLC)
Form:
solid
Quality level:
Storage condition:
OK to freeze, protect from light
产品名称
腺苷脱氨酶抑制剂, DCF, The Adenosine Deaminase Inhibitor, DCF, also referenced under CAS 53910-25-1, controls the biological activity of Adenosine Deaminase.
Quality Level
assay
≥98% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, protect from light
color
white
solubility
DMSO: 10 mg/mL, clear, colorless, water: 50 mg/mL, clear, colorless
shipped in
ambient
storage temp.
2-8°C
SMILES string
O[C@@H]1CNC=NC2=C1N=CN2[C@@H]3O[C@H](CO)[C@H](O)C3[H]
InChI
1S/C11H16N4O4/c16-3-8-6(17)1-9(19-8)15-5-14-10-7(18)2-12-4-13-11(10)15/h4-9,16-18H,1-3H2,(H,12,13)/t6-,7+,8+,9+/m0/s1
InChI key
FPVKHBSQESCIEP-JQCXWYLXSA-N
General description
一种细胞渗透性嘌呤嘧啶核苷化合物,可作为腺苷脱氨酶的高效紧密结合过渡态类似物抑制剂(ADA;对于部分纯化的人红细胞,Ki=2.5 pM,对于大鼠肝脏、大鼠肠、大鼠肝细胞瘤和人B细胞,Ki=0.48-9.1 nM)。据报道是一种免疫调节剂,对淋巴细胞具有选择性毒性。
Packaging
用惰性气体包装
Preparation Note
复溶后,等分并冷冻保存(-20°C)。储备溶液在-20°C下可稳定保存至多6个月。
Other Notes
Robak, T. 2007.Cancer Treat.Rev.33, 710.
Klohs, W.D. and Kraker, A.J., 1992.Pharmacol.Rev.44, 459.
Agarwal, R.P., et al. 1977.Biochem.Pharmacol.26, 359.
Klohs, W.D. and Kraker, A.J., 1992.Pharmacol.Rev.44, 459.
Agarwal, R.P., et al. 1977.Biochem.Pharmacol.26, 359.
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Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
毒性:有害 & 致癌/致畸性(E)
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signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 116860-10MG | 04055977223934 |
