产品名称
LiChrospher® 100 RP-18 endcapped (5 µm),
material
stainless steel column
agency
suitable for USP L1
product line
LiChrospher®
feature
endcapped
packaging
1 ea of
extent of labeling
21.6% Carbon loading
parameter
60 °C max. temp.
technique(s)
HPLC: suitable, mass spectrometry (MS): suitable (Low - Medium)
surface area
350 m2/g
matrix
fully porous particle
matrix active group
C18 bonding phase
particle size
5 μm
pore size
100 Å pore size
operating pH range
2-7.5
bulk density
200‑400 kg/m3
separation technique
reversed phase
storage temp.
no temp limit
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General description
LiChrospher® RP-18 endcapped is a reliable and versatile traditionally produced spherical silica gel carrier with revered phase properties. It is well suited for the separation of neutral, acidic and weak basic compounds.
Application
- Simultaneous quantification of delta-9-THC, THC-acid A, CBN and CBD in seized drugs using HPLC-DAD: The robustness of the LiChrospher® 60 RP-select B column is highlighted in forensic science, where it is used to accurately identify and quantify cannabinoids, demonstrating its critical role in legal and forensic analyses (Ambach et al., 2014).
- RP-HPLC separation and characterization of unknown impurities of a novel HIV-protease inhibitor Darunavir by ESI-MS and 2D NMR spectroscopy: The LiChrospher® 60 RP-select B column′s exceptional selectivity and performance are utilized to identify novel impurities in Darunavir, highlighting its application in developing more effective HIV treatments (Nageswara Rao et al., 2013).
- Quantification of pralidoxime (2-PAM) in urine by ion pair chromatography-diode array detection: Demonstrating versatility, this column was used to detect therapeutic agents in clinical settings, supporting treatment regimes for poisonings where rapid and accurate drug monitoring is essential (John et al., 2012).
Analysis Note
Application test: passes test
Pressure: ≤ 50 bar
Theoretical Plates (N/m) (Toluene): ≥ 60000
stability testing (performance): passes test
Particle Size (d10): 4.8 - 5.5 µm
Particle Size (d50): 6.5 - 7.5 µm
Particle Size (d90): 9.0 - 10.5 µm
Pressure: ≤ 50 bar
Theoretical Plates (N/m) (Toluene): ≥ 60000
stability testing (performance): passes test
Particle Size (d10): 4.8 - 5.5 µm
Particle Size (d50): 6.5 - 7.5 µm
Particle Size (d90): 9.0 - 10.5 µm
Legal Information
LiChrospher is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
11 - Combustible Solids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
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