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Merck
CN

124031

InhibitorSelect Akt/PI 3-K/mTOR Signaling Pathway Inhibitor Panel

The InhibitorSelect Akt/PI 3-K/mTOR Signaling Pathway Inhibitor Panel controls the biological activity of InhibitorSelect.

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UNSPSC Code:
12352200

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form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, desiccated (hygroscopic), protect from light

shipped in

ambient

storage temp.

−20°C

Quality Level

100

General description

A panel of 12 highly potent and selective kinase inhibitors and a negative control useful for the study of Akt/PI 3-K/mTOR signaling pathway. This panel contains the following inhibitors: 1 mg of Akt Inhibitor IV (Cat. No. 124011); 1 mg of Akt Inhibitor VIII, Isozyme-Selective, Akti-1/2 (Cat. No.124018); 5 mg of LY-294002 (Cat. No. 440202); 1 mg of LY 303511 (Cat. No. 440203); 5 mg of PDK1/Akt/Flt Dual Pathway Inhibitor (Cat. No. 521275); 1 mg of PI-103 (Cat. No. 528100); 5 mg of PI 3-Kγ Inhibitor (Cat. No. 528106); 5 mg of PI 3-Kγ Inhibitor II (Cat. No. 528108); 5 mg of PI 3-Kα Inhibitor IV (Cat. No. 528111); 5 mg of PI 3-Kα Inhibitor VIII (Cat. No. 528116); 100 µg of Rapamycin (Cat. No. 553210); 500 µg of Ro-31-8220 (Cat. No. 557520); and 1 mg of Wortmannin (Cat. No. 681675). Also provided is 15 ml of anhydrous DMSO. Supplied with a data sheet.

Packaging

Packaged under inert gas

Preparation Note

Following reconstitution, aliquot and freeze (-20°C) each inhibitor. Each inhibitor solution is stable for up to 3 months at -20°C.
Please refer to information provided on the CD for reconstitution information of individual inhibitors.

Other Notes

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Multiple Toxicity Values, refer to MSDS (O)

存储类别

10-13 - German Storage Class 10 to 13

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相关内容

PRODUCTO REGULADO POR LA SAGARPA
Human Kinome & InhibitorSelect™ Libraries

Human Kinome Poster: The InhibitorSelect™ Protein Kinase Inhibitor Libraries provide broad coverage of the human kinome as shown here. The depicted human kinome dendrogram of 518 kinases are classified into five broad groups, 90 families, and 145 subfamilies. Inhibitor coverage was assigned based upon published data related to potency (IC50, EC50, Kd, etc.) for individual kinases harvested from the literature. Colored dots denote which library contains an inhibitor with demonstrated potent activity against the designated kinase and do not necessarily reflect known specificity of the inhibitor. Coverage of lipid and atypical kinases are depicted as a separate dendrogram. As shown, Calbiochem® Protein Kinase Inhibitor Libraries cover all major kinase families including TK, CMGC, CAMK, AGC, CK1, STE, TKL, as well as Lipid or Atypical kinase families.

CARTA DE USO GENERAL 2016

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