Preparative HPLC involves much higher sample loading volumes than analytical chromatography. Consequently, greater sample throughput and separation speed are essential for optimal productivity. These criteria are best fulfilled by Chromolith^® Prep Si columns. The combination of macro and mesopores maximizes separation efficiency and flow rate, while minimizing resistance.

The revolutionary, monolithic silica with its unique combination of macropores and mesopores enables:
—Rapid separations at very low column back-pressure
—High matrix tolerance, allowing time and cost savings with simplified workflows
—Cost-savings due to extended column lifetimes

Learn more:
Brochure: Race through your Separations on Any System. Chromolith^® Monolithic Silica HPLC Columns

Pressure: ≤ 15 bar
Theoretical Plates (N/m) (2-nitroanisol): ≥ 50000
Capacity factor (2-nitroanisol): 1.0 - 2.0
Tailing (USP): 0.90 - 1.45 %
separation factor (2-nitroanisol/nitrobenzene): 3.2 - 4.0

Chromolith is a registered trademark of Merck KGaA, Darmstadt, Germany