PRAK Protein, unactive

54kDa

FUNCTION: SwissProt: Q8IW41 # Mediates stress-induced small heat shock protein 27 phosphorylation.
SIZE: 473 amino acids; 54220 Da
SUBUNIT: Interacts with SQSTM1.
SUBCELLULAR LOCATION: Cytoplasm (Probable). Nucleus. Note=Also observed in the nucleus.
TISSUE SPECIFICITY: Expressed ubiquitously.
PTM: Phosphorylated on Thr-182; which is the regulatory phosphorylation site and is located on the T-loop/loop 12.
SIMILARITY: SwissProt: Q8IW41 ## Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. & Contains 1 protein kinase domain.

Also available in 50 mg size (cat#14-335)

Stable for 6 months at -20C

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

Routinely evaluated by phosphorylation of PRAK Substrate Peptide

routinely evaluated by phosphorylation of PRAK Substrate Peptide

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