14-346-M
CHK1 Protein, active, 10 µg
Active, N-terminal GST tagged, human full length CHK1, for use in Kinase Assays.
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关于此项目
UNSPSC Code:
12352202
NACRES:
NA.32
eCl@ss:
32160405
Biological source:
human
Mol wt:
Mw 81.6 kDa
产品名称
CHK1 Protein, active, 10 µg, Active, N-terminal GST tagged, human full length CHK1, for use in Kinase Assays.
biological source
human
mol wt
Mw 81.6 kDa
manufacturer/tradename
Upstate®
technique(s)
activity assay: suitable (kinase)
NCBI accession no.
UniProt accession no.
Quality Level
Gene Information
human ... CHEK1(1111)
Analysis Note
routinely evaluated by phosphorylation of the CHKtide substrate peptide
Biochem/physiol Actions
Protein Target: CHK1
Target Sub-Family: CAMK
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
N-terminal GST tagged, human full length CHK1
Product Source: expressed in SF21 cells
Other Notes
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Packaging
Also available in 250 µg size --call for pricing and availability and reference catalog number 14-346M when ordering the 250 µg size.
Physical form
Glutathione-agarose
Preparation Note
1 year at -70C
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Warning
hcodes
Hazard Classifications
Skin Sens. 1
存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
B Furnari et al.
Science (New York, N.Y.), 277(5331), 1495-1497 (1997-09-05)
Arrest of the cell cycle at the G2 checkpoint, induced by DNA damage, requires inhibitory phosphorylation of the kinase Cdc2 in both fission yeast and human cells. The kinase Wee1 and the phosphatase Cdc25, which regulate Cdc2 phosphorylation, were evaluated
Y Sanchez et al.
Science (New York, N.Y.), 277(5331), 1497-1501 (1997-09-05)
In response to DNA damage, mammalian cells prevent cell cycle progression through the control of critical cell cycle regulators. A human gene was identified that encodes the protein Chk1, a homolog of the Schizosaccharomyces pombe Chk1 protein kinase, which is
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