14-459-M
Abl Protein, active, mouse, 10 µg
Active, recombinant mouse Abl, residues 27-1123, containing N-terminal His-6 tag, for use in Kinase Assays.
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关于此项目
UNSPSC Code:
12352202
NACRES:
NA.32
eCl@ss:
32160405
Biological source:
mouse
Recombinant:
expressed in baculovirus infected Sf21 cells
Mol wt:
Mw 123.5 kDa
产品名称
Abl Protein, active, mouse, 10 µg, Active, recombinant mouse Abl, residues 27-1123, containing N-terminal His-6 tag, for use in Kinase Assays.
biological source
mouse
recombinant
expressed in baculovirus infected Sf21 cells
mol wt
Mw 123.5 kDa
manufacturer/tradename
Upstate®
technique(s)
activity assay: suitable (kinase)
NCBI accession no.
UniProt accession no.
Physical form
Ni2+/NTA-agarose
Preparation Note
1 year at -70°C
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Packaging
Also available in 250 µg size --call for pricing and availability and reference catalog number 14-459M when ordering the 250 µg size.
Analysis Note
routinely evaluated by phosphorylation of Abltide
Biochem/physiol Actions
Protein Target: Abl
Target Sub-Family: TK
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
Product Source: Expressed by baculovirus in Sf21
Recombinant mouse Abl, residues 27-1123, containing N-terminal His6 tag
Other Notes
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
signalword
Warning
hcodes
Hazard Classifications
Skin Sens. 1
存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Activation of the c-Abl tyrosine kinase in the stress response to DNA-damaging agents.
Kharbanda, S, et al.
Nature, 376, 785-788 (1995)
B B Brasher et al.
The Journal of biological chemistry, 275(45), 35631-35637 (2000-08-31)
Using the specific Abl tyrosine kinase inhibitor STI 571, we purified unphosphorylated murine type IV c-Abl and measured the kinetic parameters of c-Abl tyrosine kinase activity in a solution with a peptide-based assay. Unphosphorylated c-Abl exhibited substantial peptide kinase activity
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