biological source
human
recombinant
expressed in Sf21 cells
mol wt
Mw 53 kDa
manufacturer/tradename
Upstate®
technique(s)
activity assay: suitable (kinase)
NCBI accession no.
UniProt accession no.
Quality Level
Gene Information
human ... MAPK10(5602)
General description
N-terminal His6 tagged, recombinant, full length human JNK3/SAPK1b
Product Source: expressed in Sf21 cells
Biochem/physiol Actions
Protein Target: JNK3/SAPK1b
Target Sub-Family: CMGC
Packaging
Also available in 250 µg size --call for pricing and availability and reference catalog number 14-501M when ordering the 250 µg size.
Physical form
Ni2+/NTA-agarose
Preparation Note
6 months at -70°C
Analysis Note
routinely evaluated by phosphorylation of ATF2 (amino acids 19-96)
Other Notes
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
signalword
Warning
hcodes
Hazard Classifications
Skin Sens. 1
存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Deepak Nihalani et al.
The Journal of biological chemistry, 278(31), 28694-28702 (2003-05-21)
JIP1 is a scaffold protein that assembles and facilitates the activation of the mixed lineage kinase-dependent JNK module. Results of earlier work led us to propose a model for JIP1-JNK complex regulation that predicts that under basal conditions, JIP1 maintains
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