产品名称
MEK2 Protein, inactive, 50 g, Unactive, N-terminal His6-tagged recombinant, full-length human MEK2, for use in Kinase Assays.
biological source
human
recombinant
expressed in baculovirus infected Sf21 cells
mol wt
Mw 46 kDa
manufacturer/tradename
Upstate®
technique(s)
activity assay: suitable (kinase)
NCBI accession no.
UniProt accession no.
shipped in
dry ice
Quality Level
Analysis Note
routinely evaluated by phosphorylation of MBP substrate
Biochem/physiol Actions
Protein Target: MEK2
General description
N-terminal His6-tagged recombinant, full-length human MEK2
Other Notes
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Warning
hcodes
Hazard Classifications
Skin Sens. 1
存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Seoyeon Bok et al.
Nature communications, 11(1), 5704-5704 (2020-11-13)
Neurofibromatosis type I (NF1) is characterized by prominent skeletal manifestations caused by NF1 loss. While inhibitors of the ERK activating kinases MEK1/2 are promising as a means to treat NF1, the broad blockade of the ERK pathway produced by this strategy
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