质量水平
描述
protein target TSSK2
纯化方式
(Ni2+/NTA-agarose)
技术
activity assay: suitable
UniProt登记号
基因信息
human ... TSSK2(23617)
一般描述
FUNCTION: SwissProt: Q96PF2 # Involved in the late stages of spermatogenesis, during the reconstruction of the cytoplasm (By similarity).
COFACTOR: Magnesium (By similarity).
SIZE: 358 amino acids; 40939 Da
SUBUNIT: Binds to STK22A (By similarity).
SUBCELLULAR LOCATION: Cytoplasm (By similarity).
TISSUE SPECIFICITY: Testis.
PTM: Autophosphorylated (By similarity).
DISEASE: SwissProt: Q96PF2 # May play a part in the etiology of the velocardiofacial/DiGeorge syndrome (VCFS/DGS), a developmental disorder characterized by structural and functional palate anomalies, conotruncal cardiac malformations, immunodeficiency, hypocalcemia, and typical facial anomalies. Most cases result from a deletion of chromosome 22q11.2 (the DiGeorge syndrome chromosome region, or DGCR).
SIMILARITY: SwissProt: Q96PF2 ## Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. & Contains 1 protein kinase domain.
COFACTOR: Magnesium (By similarity).
SIZE: 358 amino acids; 40939 Da
SUBUNIT: Binds to STK22A (By similarity).
SUBCELLULAR LOCATION: Cytoplasm (By similarity).
TISSUE SPECIFICITY: Testis.
PTM: Autophosphorylated (By similarity).
DISEASE: SwissProt: Q96PF2 # May play a part in the etiology of the velocardiofacial/DiGeorge syndrome (VCFS/DGS), a developmental disorder characterized by structural and functional palate anomalies, conotruncal cardiac malformations, immunodeficiency, hypocalcemia, and typical facial anomalies. Most cases result from a deletion of chromosome 22q11.2 (the DiGeorge syndrome chromosome region, or DGCR).
SIMILARITY: SwissProt: Q96PF2 ## Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. & Contains 1 protein kinase domain.
包装
Also available in 10 μg size (cat#14-632) and in bulk (cat#14-632-K).
质量
Routinely evaluated by phosphorylation of CHKtide
routinely evaluated by phosphorylation of CHKtide
物理属性
44.8kDa
储存及稳定性
6 months at -70°C
分析说明
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
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