biological source
human
Quality Segment
recombinant
expressed in baculovirus infected Sf21 cells
mol wt
Mw 38.9 kDa
manufacturer/tradename
Upstate®
technique(s)
activity assay: suitable
NCBI accession no.
UniProt accession no.
General description
C-terminal His6-tagged, recombinant, human JAK2, amino acids 808-end, expressed by baculovirus in Sf21 cells
Product Source: recombinant, human JAK2, amino acids 808-end
Application
Research Category
Inflammation & Immunology
Inflammation & Immunology
Biochem/physiol Actions
Protein Target: JAK2
Target Sub-Family: TK
Physical form
Ni2+/NTA-agarose
Preparation Note
6 months at -70°C
Analysis Note
routinely evaluated by phosphorylation of PDKtide (12-401)
Other Notes
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
signalword
Warning
hcodes
Hazard Classifications
Skin Sens. 1
存储类别
12 - Non Combustible Liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
相关内容
The Janus kinase (JAK)/signal transducers and activators of transcription (STAT) signaling pathway plays an important role in cell proliferation, cell differentiation, cell migration, and cell death. It is the principal signaling mechanism for a variety of cytokines and growth factors. Constitutive activation or dysregulation of JAK/STAT signaling can result in inflammatory disease, erythrocytosis, gigantism, and leukemia.
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 14-640M | 04053252324215 |
| 14-640 | 04053252400797 |
