DAPK2 Protein, active, 250 µg

70.6kDa

FUNCTION: SwissProt: Q9UIK4 # Calcium/calmodulin-dependent serine/threonine kinase which acts as a positive regulator of apoptosis.
COFACTOR: Magnesium.
SIZE: 370 amino acids; 42898 Da
SUBUNIT: Homodimer. Homodimerization is required for apoptotic function and is inhibited by autophosphorylation at Ser-318.
SUBCELLULAR LOCATION: Cytoplasm.
TISSUE SPECIFICITY: Ubiquitously expressed in all tissue types examined. High levels in heart, lung and skeletal muscle.
SIMILARITY: SwissProt: Q9UIK4 ## Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. DAP kinase subfamily. & Contains 1 protein kinase domain.

Also available in 10 μg size (cat#14-657) and in bulk (cat# 14-657-K).

6 months at -70°C from date of shipment

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

routinely evaluated by phosphorylation of ZIPtide (Catalog # 12-545)

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