生物来源
human
重组
expressed in baculovirus infected Sf21 cells
分子量
Mw 60.9 kDa
制造商/商品名称
Upstate®
技术
activity assay: suitable (kinase)
NCBI登记号
UniProt登记号
基因信息
human ... DAPK1(1612)
一般描述
N-terminal GST-tagged, recombinant, human DAPK1, amino acids 1-296
生化/生理作用
Protein Target: DAPK1
制备说明
stable 6 months at -70°C from date of shipment
分析说明
routinely evaluated by phosphorylation of ZIPtide (Catalog #12-545)
其他说明
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
警示用语：
Warning
危险声明
危险分类
Skin Sens. 1
储存分类代码
12 - Non Combustible Liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Anastasia V Velentza et al.
Pharmacology & therapeutics, 93(2-3), 217-224 (2002-08-23)
Death-associated protein kinase (DAPK) is a calmodulin-regulated serine/threonine protein kinase associated with neuronal cell death in animal models of disease. The recent determination of the 1.5A crystal structure of the catalytic kinase domain of DAPK, the discovery of amino acid
Epigenetic change in pituitary tumorigenesis.
Farrell, W E and Clayton, R N
Endocrine-Related Cancer, 10, 323-330 (2003)
DAP-kinase as a target for drug design in cancer and diseases associated with accelerated cell death.
Bialik, Shani and Kimchi, Adi
Seminars in cancer biology, 14, 283-294 (2004)
The DAP-kinase family of proteins: study of a novel group of calcium-regulated death-promoting kinases.
Shohat, Galit, et al.
Biochimica et Biophysica Acta, 1600, 45-50 (2002)
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