Quality Level
Gene Information
human ... STK24(8428)
General description
61.2kDa
FUNCTION: SwissProt: Q9Y6E0 # Protein kinase that act on both serine and threonine residues.
COFACTOR: Manganese. Only isoform A requires manganese.
SIZE: 443 amino acids; 49308 Da
SUBCELLULAR LOCATION: Cytoplasm (By similarity).
TISSUE SPECIFICITY: Isoform A is ubiquitous. Isoform B is expressed in brain with high expression in hippocampus and cerebral cortex.
PTM: Autophosphorylated. Isoform B is activated by phosphorylation by PKA.
SIMILARITY: SwissProt: Q9Y6E0 ## Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. & Contains 1 protein kinase domain.
COFACTOR: Manganese. Only isoform A requires manganese.
SIZE: 443 amino acids; 49308 Da
SUBCELLULAR LOCATION: Cytoplasm (By similarity).
TISSUE SPECIFICITY: Isoform A is ubiquitous. Isoform B is expressed in brain with high expression in hippocampus and cerebral cortex.
PTM: Autophosphorylated. Isoform B is activated by phosphorylation by PKA.
SIMILARITY: SwissProt: Q9Y6E0 ## Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. & Contains 1 protein kinase domain.
Packaging
Also available in 10 μg size (cat#14-695) and in bulk (cat#14-695-K).
Preparation Note
stable for 6 months at -70°C from date of shipment
Analysis Note
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Routinely evaluated by phosphorylation of PKCtide (Catalog# 12-536)
routinely evaluated by phosphorylation of PKCtide (Catalog# 12-536)
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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