61.2kDa

FUNCTION: SwissProt: Q9Y6E0 # Protein kinase that act on both serine and threonine residues.
COFACTOR: Manganese. Only isoform A requires manganese.
SIZE: 443 amino acids; 49308 Da
SUBCELLULAR LOCATION: Cytoplasm (By similarity).
TISSUE SPECIFICITY: Isoform A is ubiquitous. Isoform B is expressed in brain with high expression in hippocampus and cerebral cortex.
PTM: Autophosphorylated. Isoform B is activated by phosphorylation by PKA.
SIMILARITY: SwissProt: Q9Y6E0 ## Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. & Contains 1 protein kinase domain.

Also available in 10 μg size (cat#14-695) and in bulk (cat#14-695-K).

stable for 6 months at -70°C from date of shipment

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

Routinely evaluated by phosphorylation of PKCtide (Catalog# 12-536)

routinely evaluated by phosphorylation of PKCtide (Catalog# 12-536)

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