FAK Protein, active, 10 µg

产品名称

FAK Protein, active, 10 µg, Active, N-terminal 6His-tagged, recombinant, human FAK, amino acids 411-686, for use in Kinase Assays.

biological source

human

recombinant

expressed in baculovirus infected Sf21 cells

product line

Upstate^®

specific activity

(For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.)

mol wt

M_w 35.5 kDa

purified by

(Ni²⁺/NTA-agarose)

species reactivity

human

manufacturer/tradename

Upstate^®

technique(s)

activity assay: suitable (kinase)

accession no.

 (FUNCTION: SwissProt: Q05397 # Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Plays a potential role in oncogenic transformations resulting in increased kinase activity. )
NM_005607.3

NCBI accession no.

NM_005607.3
NM_153831.2

UniProt accession no.

Q05397

relevant disease(s)

obesity; metabolic disorders

Quality Level

100

Gene Information

human ... PTK2(5747)