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Merck
CN

1.50848

LiChrospher® 100 RP-18 endcapped (10 µm) HPLC Columns

L x I.D. 250 mm x 4 mm, LiChroCART HPLC cartridge, manuCART holder required for use

别名:

TM=["LiChrospher"] C18 TM=["LICHROCART"] cartridge for HPLC

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UNSPSC Code:
41115709
NACRES:
SB.52
Particle size:
10 μm
Matrix active group:
C18 bonding phase
Pore size:
100 Å pore size
Matrix:
fully porous particle
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产品名称

LiChrospher® 100 RP-18 endcapped (10 µm) LiChroCART 250-4, suitable for HPLC

material

stainless steel column

agency

suitable for USP L1

product line

LiChrospher®

feature

endcapped

packaging

1 ea of

extent of labeling

21.6% Carbon loading

parameter

250 bar pressure, 60 °C max. temp.

technique(s)

HPLC: suitable, mass spectrometry (MS): suitable (Low - Medium)

column L × I.D.

25 cm × 4 mm

surface area

350 m2/g

matrix

fully porous particle

matrix active group

C18 bonding phase

particle size

10 μm

pore size

100 Å pore size

operating pH range

2-7.5

separation technique

reversed phase

storage temp.

no temp limit

Quality Level

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General description

HPLC cartridge
LiChrospher® RP-18 endcapped is a reliable and versatile traditionally produced spherical silica gel carrier with C-18 endcapped reversed phase properties. It is well suited for the separation of neutral, acidic and weak basic compounds. This sorbent is packed into a LiChroCART 250-4 HPLC cartridge. The connection to the HPLC system is being accomplished by use of the manu-CART NT cartrige holder (1.51486).

Application


  • Integration of Solid-Phase Extraction and Reversed-Phase Chromatography in Single Protein-Coated Columns for Direct Injection of Bupivacaine in Human Serum: This study highlights the use of the LiChrosorb® RP-8 HPLC column in a novel method integrating solid-phase extraction with reversed-phase chromatography. This approach significantly enhances the efficiency and accuracy of bupivacaine analysis in human serum, underscoring the column′s utility in clinical and pharmaceutical settings. The research demonstrates the column′s high performance in complex sample matrices, making it an invaluable tool for analytical chemists and researchers in drug monitoring and pharmacokinetics (Zarad et al., 2020).

Analysis Note

Pressure: ≤ 40 bar
Theoretical Plates (N/m) (Toluene): ≥ 20000
Symmetry (Toluene): 0.8 - 1.4
Capacity factor (Toluene): 1.5 - 3.0

Legal Information

LICHROCART is a trademark of Merck KGaA, Darmstadt, Germany
LiChrosorb is a registered trademark of Merck KGaA, Darmstadt, Germany
LiChrospher is a registered trademark of Merck KGaA, Darmstadt, Germany

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