16-229
Anti-Cortactin (p80/85) Antibody, clone 4F11, Alexa Fluor™ 555
clone 4F11, Upstate®, from mouse
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eCl@ss:
32160702
UNSPSC Code:
12352203
Conjugate:
ALEXA FLUOR™ 555
Clone:
4F11, monoclonal
Application:
FACS, ICC, IF, WB
Citations:
14
biological source
mouse
conjugate
ALEXA FLUOR™ 555
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
4F11, monoclonal
species reactivity
bovine, human, rat, mouse, avian, hamster
manufacturer/tradename
Upstate®
technique(s)
flow cytometry: suitable, immunocytochemistry: suitable, immunofluorescence: suitable, western blot: suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... CTTN(2017)
General description
Mr 80kDa and in avian cells, Mr 80kDa and 85kDa
Immunogen
Mixture of affinity-purified tyrosine phosphoproteins from chick embryo fibroblasts expressing activated pp60src
Application
Anti-Cortactin (p80/85) Antibody, clone 4F11, Alexa Fluor 555 detects level of Cortactin (p80/85) & has been published & validated for use in FC, IF, WB & IC.
Research Category
Cell Structure
Cell Structure
Research Sub Category
Cytoskeleton
Cytoskeleton
Biochem/physiol Actions
Recognizes Cortactin in rodent and human cells
Physical form
Protein G Purified
Preparation Note
1 year at 4°C from date of shipment
Analysis Note
Routinely evaluated by immunoblot.
Legal Information
ALEXA FLUOR is a trademark of Life Technologies
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Alexa Fluor™ is a registered trademark of Molecular Probes, Inc.
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Kelly M Bailey et al.
Neoplasia (New York, N.Y.), 18(8), 480-488 (2016-08-28)
Metastatic Ewing sarcoma has a very poor prognosis and therefore new investigations into the biologic drivers of metastatic progression are key to finding new therapeutic approaches. The tumor microenvironment is highly dynamic, leading to exposure of different regions of a
Khemraj Singh Baghel et al.
Oncoimmunology, 5(7), e1196299-e1196299 (2016-09-14)
The potential of a tumor cell to metastasize profoundly depends on its microenvironment, or "niche" interactions with local components. Tumor-associated-macrophages (TAMs) are the most abundant subpopulation of tumor stroma and represent a key component of tumor microenvironment. The dynamic interaction
Cortactin phosphorylation as a switch for actin cytoskeletal network and cell dynamics control.
Lua, Bee Leng and Low, Boon Chuan
Febs Letters, 579, 577-585 (2005)
Cortactin: an Achilles' heel of the actin cytoskeleton targeted by pathogens.
Selbach, Matthias and Backert, Steffen
Trends in Microbiology, 13, 181-189 (2005)
Actions by actin: reciprocal regulation of cortactin activity by tyrosine kinases and F-actin.
Gunst, Susan J
The Biochemical Journal, 380, e7-e8 (2004)
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