biological source
mouse
conjugate
ALEXA FLUOR™ 488
antibody form
purified antibody
antibody product type
primary antibodies
clone
SKB1, monoclonal
species reactivity
mouse, rat, human
manufacturer/tradename
Upstate®
technique(s)
flow cytometry: suitable, immunocytochemistry: suitable, immunofluorescence: suitable, western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
mouse ... Akt1(11651)
General description
60 kDa
Immunogen
GST-fusion protein corresponding to residues 1-149 of human Akt1. Clone SKB1.
Application
Anti-Akt/PKB Antibody, PH Domain, clone SKB1, Alexa Fluor 488 is an antibody against Akt/PKB for use in FC, IC, IF & WB.
Biochem/physiol Actions
Recognizes Akt1/PKBα > Akt2/PKBβ (30%) > Akt3/PKBγ (weak to none) based on immunoblot analysis using 100ng recombinant fusion protein for each isoform.
Analysis Note
Routinely evaluated by Immunocytochemistry and Flow Cytometry
Legal Information
ALEXA FLUOR is a trademark of Life Technologies
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
10 - Combustible liquids
法规信息
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Elke Butt et al.
Cells, 9(2) (2020-02-23)
The serine/threonine protein kinase AKT1 is a downstream target of the chemokine receptor 4 (CXCR4), and both proteins play a central role in the modulation of diverse cellular processes, including proliferation and cell survival. While in chronic myeloid leukemia (CML)
Chanya Inprasit et al.
International journal of molecular medicine, 45(3), 779-792 (2020-01-11)
Obesity is a global health problem affecting the general population. Acupoint catgut embedding (ACE) is an alternative treatment that involves the implantation of absorbable catgut suture at acupoints. The transient receptor vanilloid member 1 (TRPV1) is a calcium ion channel
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