Apolipoprotein C-II, Human Plasma, Very Low-Density Lipoprotein

Native apolipoprotein C-II from human plasma. Found primarily in VLDL and chylomicrons. Functions as a cofactor for lipoprotein lipase. Elevated serum levels of Apo C-II are common in type I, III, IV, and V hyperlipoproteinemia. Low serum concentrations of Apo C-II are indicative of nephrotic syndrome (Tangier’s Disease).

Lyophilized from 10 mM NH₄HCO₃, pH 7.4.

Please refer to vial label for lot-specific volume prior to lyophilization.

Brunzell, J.D. 1989. in The Metabolic Basis of Inherited Disease,6th Edition (Scriver, G.R., ed.) p. 1165, McGraw Hill, New York.
Le, N.A., et al. 1988. J. Lipid Res. 29, 669.
Jackson, R.L., and Holdsworth, G. 1986. Methods Enzymol.128, Chapter 14.

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Toxicity: Standard Handling (A)