182517
Inactive control, CK-689
≥95% (HPLC), Arp2/3 Complex Inhibitor, solid
别名:
Arp2/3复合物抑制剂I，失活对照，CK-689
产品名称
Arp2/3复合物抑制剂I，失活对照，CK-689, The Arp2/3 Complex Inhibitor I, Inactive Control, CK-689, also referenced under CAS 170930-46-8, controls the biological activity of Arp2/3. This small molecule/inhibitor is primarily used for Cell Structure applications.
质量水平
方案
≥95% (HPLC)
表单
solid
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
protect from light
颜色
off-white
溶解性
DMSO: 50 mg/mL
运输
ambient
储存温度
2-8°C
相关类别
一般描述
在基于细胞和无细胞的实验中，细胞可渗透的吲哚基-甲氧基乙酰胺均不显示Arp2/3抑制活性，并且可作为CK-666（目录编号182515）的无活性对照。
包装
用惰性气体包装
制备说明
复溶后，等分并冷冻保存（-20°C）。储备液在-20°C条件下可稳定保存6个月。
其他说明
Nolen, B.J., et al. 2009.Nature460, 1031.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
毒性：标准处理（A）
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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Antigen-induced B-cell receptor (BCR) signaling is critical for initiating and regulating B-cell activation. The actin cytoskeleton plays essential roles in BCR signaling. Upon encountering cell-surface antigens, actin-driven B-cell spreading amplifies signaling, while B-cell contraction following spreading leads to signal attenuation.
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