form
solid
Quality Level
manufacturer/tradename
Upstate®
technique(s)
activity assay: suitable (kinase)
shipped in
wet ice
Application
适合用作丝氨酸/苏氨酸特异性蛋白磷酸酶的抑制剂。
Preparation Note
冻干：在4°C下可保存2年；再水化：在-20°C下可保存6个月
Analysis Note
在激酶测定中常规评估为抑制剂。
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Skin Irrit. 2
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
法规信息
高风险级别生物产品--毒素类产品
此项目有
Okadaic acid. Protein phosphatase inhibition and muscle contractile effects.
Takai, A
Journal of Muscle Research and Cell Motility, 9, 563-565 (1988)
F M Amara et al.
The Journal of biological chemistry, 271(33), 20126-20131 (1996-08-16)
Mammalian ribonucleotide reductase is a highly regulated activity essential for DNA synthesis and repair. The 3'-untranslated region (3'-UTR) of mammalian ribonucleotide reductase R2 mRNA has been implicated in the tumor promoter, 12-O-tetradecanoylphorbol-13-acetate-mediated stabilization of mouse BALB/c 3T3 R2 message. We
E G Mimnaugh et al.
The Journal of biological chemistry, 270(48), 28654-28659 (1995-12-01)
The abundant, cytoplasmic 90-kDa heat-shock protein associates transiently with the Rous sarcoma virus oncogenic protein tyrosine kinase, pp60v-src, directs its cellular trafficking and negatively regulates its kinase activity. Here we report that the serine/threonine phosphatase inhibitor, okadaic acid, destabilized the
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 19-130 | 04053252731921 |
| SYNC109130-1EA | 04061832185750 |