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Merck
CN

19-141

H-89,二盐酸盐

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UNSPSC Code:
12352302
NACRES:
NA.41
eCl@ss:
32160405
Form:
solid
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form

solid

manufacturer/tradename

Upstate®

technique(s)

activity assay: suitable (kinase)

shipped in

wet ice

Quality Level

Application

PKA的强效选择性抑制剂。

Biochem/physiol Actions

抑制剂种类:激酶

Physical form

冻干粉末

Preparation Note

在-20°C干燥室中保存2年。

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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F J Johannes et al.
European journal of biochemistry, 227(1-2), 303-307 (1995-01-15)
In order to investigate regulatory mechanisms and to identify potential substrates of a novel member of the protein kinase C (PKC) family, PKC mu, specific antibodies have been raised against unique amino- and carboxy-terminal regions. PKC mu kinase activity was
T Chijiwa et al.
The Journal of biological chemistry, 265(9), 5267-5272 (1990-03-25)
A newly synthesized isoquinolinesulfonamide, H-89 (N-[2-(p-bromocinnamylamino)ethyl]-5-isoquinoline-sulfonamide), was shown to have a potent and selective inhibitory action against cyclic AMP-dependent protein kinase (protein kinase A), with an inhibition constant of 0.048 +/- 0.008 microM. H-89 exhibited weak inhibitory action against other

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