form
liquid
Quality Level
manufacturer/tradename
Upstate®
technique(s)
western blot: suitable
shipped in
dry ice
General description
过氧亚硝酸盐（ONOO−）是一种强效氧化剂，由一氧化氮和超氧化物碰撞形成。
Application
过氧亚硝酸盐可用于诱导鼠大脑中的周细胞收缩。在免疫组织化学研究中，它已用于制备硝化蛋白标准品阳性对照。
Biochem/physiol Actions
过氧亚硝酸盐（ONOO−）具有杀菌活性。它促进细胞死亡，并有助于信号转导过程、线粒体功能和细胞凋亡途径。过氧亚硝酸盐的形成与各种疾病（包括血管疾病、缺血-再灌注损伤、循环休克、炎症、疼痛和神经退行性病变）的发展有关。
Physical form
0.3M NaOH
Analysis Note
通过处理未刺激的A431细胞进行常规评估。
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Met. Corr. 1 - Skin Irrit. 2
flash_point_f
Not applicable
flash_point_c
Not applicable
存储类别
12 - Non Combustible Liquids
Csaba Szabó et al.
Nature reviews. Drug discovery, 6(8), 662-680 (2007-08-02)
Peroxynitrite--the product of the diffusion-controlled reaction of nitric oxide with superoxide radical--is a short-lived oxidant species that is a potent inducer of cell death. Conditions in which the reaction products of peroxynitrite have been detected and in which pharmacological inhibition
Oxidative chemistry of peroxynitrite.
Beckman, J S, et al.
Test, 233, 229-240 (1994)
Hongjun Jin et al.
Current protocols in toxicology, Chapter 17, Unit 17-Unit 17 (2012-04-19)
Reactive nitrogen species (RNS) and reactive oxygen species (ROS) are derived as a result of inflammation and oxidative stress and can result in protein modifications. As such, these protein modifications are used as biomarkers for inflammation and oxidative stress. In
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 20-107 | 04053252671265 |
| Z114014-144EA | 04061832325828 |
| Z114014-12EA | 04061832325811 |