General description
过氧亚硝酸盐（ONOO−）是一种强效氧化剂，由一氧化氮和超氧化物碰撞形成。
Application
过氧亚硝酸盐可用于诱导鼠大脑中的周细胞收缩。在免疫组织化学研究中，它已用于制备硝化蛋白标准品阳性对照。
Biochem/physiol Actions
过氧亚硝酸盐（ONOO−）具有杀菌活性。它促进细胞死亡，并有助于信号转导过程、线粒体功能和细胞凋亡途径。过氧亚硝酸盐的形成与各种疾病（包括血管疾病、缺血-再灌注损伤、循环休克、炎症、疼痛和神经退行性病变）的发展有关。
Physical form
0.3M NaOH
Analysis Note
通过处理未刺激的A431细胞进行常规评估。
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Met. Corr. 1 - Skin Irrit. 2
存储类别
8B - Non-combustible corrosive hazardous materials
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
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Peroxynitrite--the product of the diffusion-controlled reaction of nitric oxide with superoxide radical--is a short-lived oxidant species that is a potent inducer of cell death. Conditions in which the reaction products of peroxynitrite have been detected and in which pharmacological inhibition
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Peroxynitrite is a strong oxidant formed by macrophages and potentially by other cells that produce nitric oxide and superoxide. Peroxynitrite was highly bactericidal, killing Escherichia coli in direct proportion to its concentration with an LD50 of 250 microM at 37
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Nitric oxide (NO) is a reactive cell signal that controls vascular tone and is generated by inducible (iNOS), endothelial (eNOS) and neuronal (nNOS) NO synthase (NOS). We hypothesized that NO could be important for growth of thyroid tumors and tested
Pathological implications of nitric oxide, superoxide and peroxynitrite formation.
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Reactive nitrogen species (RNS) and reactive oxygen species (ROS) are derived as a result of inflammation and oxidative stress and can result in protein modifications. As such, these protein modifications are used as biomarkers for inflammation and oxidative stress. In
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