203350
Blasticidin S hydrochloride
from Streptomyces griseochromogenes, ≥98% (HPLC), powder, protein syntheis inhibitor, Calbiochem®
别名:
杀稻瘟菌素S，盐酸盐，灰色产色链霉菌
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关于此项目
经验公式（希尔记法）:
C17H26N8O5 · xHCl
化学文摘社编号:
分子量:
422.44 (free base basis)
UNSPSC Code:
51286700
NACRES:
NA.77
MDL number:
产品名称
杀稻瘟菌素S，盐酸盐，灰色产色链霉菌,
SMILES string
Cl.N2(C=CC(=NC2=O)N)[C@@H]1O[C@@H]([C@H](C=C1)NC(=O)C[C@@H](N)CCN(C)\C(=N\[H])\N)C(=O)O
InChI
1S/C17H26N8O5.ClH/c1-24(16(20)21)6-4-9(18)8-12(26)22-10-2-3-13(30-14(10)15(27)28)25-7-5-11(19)23-17(25)29;/h2-3,5,7,9-10,13-14H,4,6,8,18H2,1H3,(H3,20,21)(H,22,26)(H,27,28)(H2,19,23,29);1H/t9-,10-,13+,14-;/m0./s1
InChI key
YQXYQOXRCNEATG-NMQKUDMSSA-N
assay
≥98% (HPLC)
form
powder
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
desiccated (hygroscopic)
color
white to off-white
shipped in
ambient
storage temp.
2-8°C
Quality Level
Biochem/physiol Actions
首要靶标
蛋白质合成
蛋白质合成
Disclaimer
毒性：高毒性（H）
General description
在原核生物和真核生物中均可特异性抑制蛋白质合成的核苷抗生素。适用于选择携带有杀稻瘟菌素抗性质粒的细胞。杀稻瘟菌素抗性是由杀稻瘟菌素S脱氨酶基因（蜡状芽孢杆菌的bsr或土曲霉的BSD）所赋予的，其产物可将杀稻瘟菌素S转化为无毒的脱氨基羟基衍生物。
Other Notes
Kimura, M., et al. 1994.Biochim.Biophys.Acta1219, 653.
Kimura, M., et al. 1994, Mol.Gen.Genet.242, 121.
Kojima, N., et al. 1994.J. Biol. Chem.269, 30451.
Kudo, T., et al. 1994.J. Immunol. Methods177, 17.
Sutoh, K. 1993.Plasmid30, 150.
Izumi, M., et al. 1991.Exp.Cell Res.197, 229.
Yamaguchi, H., et al. 1965.J. Biol. Chem.57, 667.
Takeuchi, S., et al. 1958.J. Antibiot.11, 1.
Kimura, M., et al. 1994, Mol.Gen.Genet.242, 121.
Kojima, N., et al. 1994.J. Biol. Chem.269, 30451.
Kudo, T., et al. 1994.J. Immunol. Methods177, 17.
Sutoh, K. 1993.Plasmid30, 150.
Izumi, M., et al. 1991.Exp.Cell Res.197, 229.
Yamaguchi, H., et al. 1965.J. Biol. Chem.57, 667.
Takeuchi, S., et al. 1958.J. Antibiot.11, 1.
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Preparation Note
溶解后，等分并冷冻保存（-20°C）。水相的储备液（pH ≤7）可在-20°C最长稳定1年。避免碱性pH。避免反复冻融；当将分装的溶液解冻后，未用完的部分应丢弃。
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 1 Oral
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
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