Name: 8-Bromoguanosine 3′,5′-cyclic monophosphate sodium salt
Brand: MM

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About This Item

经验公式（希尔记法）:

C₁₀H₁₀BrN₅O₇P · Na

CAS Number:

51116-01-9

分子量:

446.08

MDL编号:

MFCD00070128

UNSPSC代码:

41106305

NACRES:

NA.77

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Product Name

Guanosine 3′,5′-cyclic Monophosphate, 8-Bromo-, Sodium Salt, Cell-permeable cGMP analog that is more resistant to phosphodiesterases than cGMP.

质量水平

100

方案

≥98% (HPLC)

表单

solid

制造商/商品名称

Calbiochem^®

储存条件

OK to freeze
desiccated

颜色

white

溶解性

water: 200 mg/mL

运输

ambient

储存温度

−20°C

SMILES字符串

[P]1(=O)(O[C@@H]2[C@H](O[C@H]([C@@H]2O)[n]3c4[nH]c(n[c](c4nc3Br)=O)N)CO1)O

InChI

1S/C10H11BrN5O7P/c11-9-13-3-6(14-10(12)15-7(3)18)16(9)8-4(17)5-2(22-8)1-21-24(19,20)23-5/h2,4-5,8,17H,1H2,(H,19,20)(H3,12,14,15,18)/t2-,4-,5-,8-/m1/s1

InChI key

YUFCOOWNNHGGOD-UMMCILCDSA-N

一般描述

Cell-permeable cGMP analog that is more resistant to phosphodiesterases than cGMP. Preferentially activates protein kinase G. Inhibits thrombin-stimulated arachidonic acid release in human platelets.

生化/生理作用

Cell permeable: yes

Primary Target
protein kinase G

Product does not compete with ATP.

Reversible: no

包装

Packaged under inert gas

制备说明

Following reconstitution, aliquot and freeze (-20°C). Aqueous stock solutions are stable for up to 1 week at -20°C.

其他说明

Kwak, B.R., and Jongsma, H.J. 1996. Mol. Cell. Biochem. 157, 93.
Perreault, T., and DeMarte, J. 1993. Am. J. Physiol. 264, H302.
Ruth, P., et al. 1991. Eur. J. Biochem.202, 1339.
Schwarzschild, M.A., and Zigmond, R.E. 1991. J. Neurochem.56, 400.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Toxicity: Standard Handling (A)

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)