208724
钙蛋白酶抑制剂IV
The Calpain Inhibitor IV controls the biological activity of Calpain. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
别名:
钙蛋白酶抑制剂IV, Z-LLY-FMK
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关于此项目
经验公式（希尔记法）:
C30H40FN3O6
分子量:
557.65
NACRES:
NA.77
UNSPSC Code:
12352200
Quality Level
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, desiccated
color
white to pale yellow
solubility
DMSO: 25 mg/mL
shipped in
ambient
storage temp.
−20°C
General description
一种有效的，细胞可渗透且不可逆的钙蛋白酶II抑制剂（k2 = 28,900 M-1s-1）。还用作组织蛋白酶L的抑制剂（k2 = 680,000 M-1s-1）。
Biochem/physiol Actions
主要靶标
钙蛋白酶2
钙蛋白酶2
产物不与ATP竞争。
可逆：否
细胞可渗透性：是
钙蛋白酶II的抑制中，k₂ = 28,900 M⁻¹s⁻¹ ；组织蛋白酶L的抑制中，k2 = 680,000 M⁻¹s⁻¹
Preparation Note
复溶后，等分并冷冻保存（-20°C）。储备液在-20°C条件下可稳定保存6个月。
Analysis Note
TLC测定单个斑点
Other Notes
Dutt, P., et al. 1998.FEBS Lett.436, 367.
Angliker, H., et al. 1992.J. Med. Chem. 35, 216.
Angliker, H., et al. 1992.J. Med. Chem. 35, 216.
Z-Leu-Leu-Tyr-CH₂F
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
毒性：标准处理（A）
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 208724-1MG | 04055977202694 |